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The Structure of Neisseria meningitidis Lipid A Determines Outcome in Experimental Meningococcal Disease
Lipopolysaccharide (LPS), a major component of the meningococcal outer membrane, is sensed by the host through activation of Toll-like receptor 4 (TLR4). Recently, we demonstrated that a surprisingly large fraction of Neisseria meningitidis disease isolates are lipid A mutants, due to inactivating m...
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| Główni autorzy: | , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society for Microbiology (ASM)
2010
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2897371/ https://ncbi.nlm.nih.gov/pubmed/20439476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01311-09 |
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