Lipopolysaccharide Engineering in Neisseria meningitidis: STRUCTURAL ANALYSIS OF DIFFERENT PENTAACYL LIPID A MUTANTS AND COMPARISON OF THEIR MODIFIED AGONIST PROPERTIES

Por Pupo, Elder, Hamstra, Hendrik-Jan, Meiring, Hugo, van der Ley, Peter
Publicado em 2014

Emerging Bordetella pertussis Strains Induce Enhanced Signaling of Human Pattern Recognition Receptors TLR2, NOD2 and Secretion of IL-10 by Dendritic Cells

Por Hovingh, Elise S., van Gent, Marjolein, Hamstra, Hendrik-Jan, Demkes, Marc, Mooi, Frits R., Pinelli, Elena
Publicado no PLoS One (2017)

Immunogenicity of Outer Membrane Proteins in a Lipopolysaccharide-Deficient Mutant of Neisseria meningitidis: Influence of Adjuvants on the Immune Response

Por Steeghs, Liana, Kuipers, Betsy, Hamstra, Hendrik Jan, Kersten, Gideon, van Alphen, Loek, van der Ley, Peter
Publicado em 1999

Coincorporation of LpxL1 and PagL Mutant Lipopolysaccharides into Liposomes with Neisseria meningitidis Opacity Protein: Influence on Endotoxic and Adjuvant Activity

Por Arenas, Jesús, van Dijken, Harry, Kuipers, Betsy, Hamstra, Hendrik Jan, Tommassen, Jan, van der Ley, Peter
Publicado em 2010

Modification of Lipid A Biosynthesis in Neisseria meningitidis lpxL Mutants: Influence on Lipopolysaccharide Structure, Toxicity, and Adjuvant Activity

Por van der Ley, Peter, Steeghs, Liana, Hamstra, Hendrik Jan, ten Hove, Jan, Zomer, Bert, van Alphen, Loek
Publicado em 2001

LOS oligosaccharide modification enhances dendritic cell responses to meningococcal native outer membrane vesicles expressing a non-toxic lipid A

Por Jones, Hannah E, Copland, Alastair, Hamstra, Hendrik Jan, Cohen, Jonathan, Brown, Jeremy, Klein, Nigel, van der Ley, Peter, Dixon, Garth
Publicado em 2014

Expression of the Lipopolysaccharide-Modifying Enzymes PagP and PagL Modulates the Endotoxic Activity of Bordetella pertussis

Por Geurtsen, Jeroen, Steeghs, Liana, Hamstra, Hendrik-Jan, ten Hove, Jan, de Haan, Alex, Kuipers, Betsy, Tommassen, Jan, van der Ley, Peter
Publicado em 2006

Relative Immunogenicity of PorA Subtypes in a Multivalent Neisseria meningitidis Vaccine Is Not Dependent on Presentation Form

Por Luijkx, Thomas A., van Dijken, Harry, Hamstra, Hendrik-Jan, Kuipers, Betsy, van der Ley, Peter, van Alphen, Loek, van den Dobbelsteen, Germie
Publicado em 2003

The Structure of Neisseria meningitidis Lipid A Determines Outcome in Experimental Meningococcal Disease

Por Fransen, Floris, Hamstra, Hendrik Jan, Boog, Claire J., van Putten, Jos P., van den Dobbelsteen, Germie P. J. M., van der Ley, Peter
Publicado em 2010

Reply to Moran: Modification of Campylobacter jejuni Lipid A

Por van Mourik, Andries, Steeghs, Liana, van Laar, Jacoline, Meiring, Hugo D., Hamstra, Hendrik-Jan, van Putten, Jos P. M., Wösten, Marc M. S. M.
Publicado em 2010

Altered Linkage of Hydroxyacyl Chains in Lipid A of Campylobacter jejuni Reduces TLR4 Activation and Antimicrobial Resistance

Por van Mourik, Andries, Steeghs, Liana, van Laar, Jacoline, Meiring, Hugo D., Hamstra, Hendrik-Jan, van Putten, Jos P. M., Wösten, Marc M. S. M.
Publicado em 2010

Meningococcal Outer Membrane Vesicle Composition-Dependent Activation of the Innate Immune Response

Por Zariri, Afshin, Beskers, Joep, van de Waterbeemd, Bas, Hamstra, Hendrik Jan, Bindels, Tim H. E., van Riet, Elly, van Putten, Jos P. M., van der Ley, Peter
Publicado no Infect Immun (2016)

Expression of phosphofructokinase in Neisseria meningitidis

Por Baart, Gino J. E., Langenhof, Marc, van de Waterbeemd, Bas, Hamstra, Hendrik-Jan, Zomer, Bert, van der Pol, Leo A., Beuvery, E. C., Tramper, Johannes, Martens, Dirk E.
Publicado em 2010

Identification of a Novel Lipopolysaccharide Core Biosynthesis Gene Cluster in Bordetella pertussis, and Influence of Core Structure and Lipid A Glucosamine Substitution on Endotox...

Por Geurtsen, Jeroen, Dzieciatkowska, Monika, Steeghs, Liana, Hamstra, Hendrik-Jan, Boleij, Johanna, Broen, Kelly, Akkerman, Grietsje, el Hassan, Hassan, Li, Jianjun, Richards, James C., Tommassen, Jan, van der Ley, Peter
Publicado em 2009

Naturally Occurring Lipid A Mutants in Neisseria meningitidis from Patients with Invasive Meningococcal Disease Are Associated with Reduced Coagulopathy

Por Fransen, Floris, Heckenberg, Sebastiaan G. B., Hamstra, Hendrik Jan, Feller, Moniek, Boog, Claire J. P., van Putten, Jos P. M., van de Beek, Diederik, van der Ende, Arie, van der Ley, Peter
Publicado em 2009

Prevalence and Clinical Course in Invasive Infections with Meningococcal Endotoxin Variants

Por Rodenburg, Gerwin D., Fransen, Floris, Bogaert, Debby, Schipper, Kim, Groenwold, Rolf H. H., Hamstra, Hendrik Jan, Westerhuis, Brenda M., van de Beek, Diederik, van der Ley, Peter, Sanders, Elisabeth A. M., van der Ende, Arie
Publicado em 2012

Bordetella pertussis Naturally Occurring Isolates with Altered Lipooligosaccharide Structure Fail To Fully Mature Human Dendritic Cells

Por Brummelman, Jolanda, Veerman, Rosanne E., Hamstra, Hendrik Jan, Deuss, Anna J. M., Schuijt, Tim J., Sloots, Arjen, Kuipers, Betsy, van Els, Cécile A. C. M., van der Ley, Peter, Mooi, Frits R., Han, Wanda G. H., Pinelli, Elena
Publicado no Infect Immun (2014)