Altered Linkage of Hydroxyacyl Chains in Lipid A of Campylobacter jejuni Reduces TLR4 Activation and Antimicrobial Resistance

Modification of the lipid A moiety of bacterial lipopolysaccharide influences cell wall properties, endotoxic activity, and bacterial resistance to antimicrobial peptides. Known modifications are variation in the number or length of acyl chains and/or attached phosphoryl groups. Here we identified t...

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Bibliografske podrobnosti
Main Authors: van Mourik, Andries, Steeghs, Liana, van Laar, Jacoline, Meiring, Hugo D., Hamstra, Hendrik-Jan, van Putten, Jos P. M., Wösten, Marc M. S. M.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2010
Teme:
Glycobiology and Extracellular Matrices
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2871450/
https://ncbi.nlm.nih.gov/pubmed/20351099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.102061
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