Variable-Internal-Stores models of microbial growth and metabolism with dynamic allocation of cellular resources

Por Nev, Olga A., van den Berg, Hugo A.
Publicado no J Math Biol (2016)

Tricks with tetramers: how to get the most from multimeric peptide–MHC

Por Wooldridge, Linda, Lissina, Anna, Cole, David K, van den Berg, Hugo A, Price, David A, Sewell, Andrew K
Publicado em 2009

Spatial heterogeneity enhances and modulates excitability in a mathematical model of the myometrium

Por Sheldon, Rachel E., Baghdadi, Marc, McCloskey, Conor, Blanks, Andrew M., Shmygol, Anatoly, van den Berg, Hugo A.
Publicado em 2013

Reconstruction of Cell Surface Densities of Ion Pumps, Exchangers, and Channels from mRNA Expression, Conductance Kinetics, Whole-Cell Calcium, and Current-Clamp Voltage Recordings...

Por Atia, Jolene, McCloskey, Conor, Shmygol, Anatoly S., Rand, David A., van den Berg, Hugo A., Blanks, Andrew M.
Publicado no PLoS Comput Biol (2016)

A computational method for three-dimensional reconstruction of the microarchitecture of myometrial smooth muscle from histological sections

Por Lutton, E. Josiah, Lammers, Wim J. E. P., James, Sean, van den Berg, Hugo A., Blanks, Andrew M.
Publicado no PLoS One (2017)

CD8 CONTROLS T CELL CROSSREACTIVITY

Por Wooldridge, Linda, Laugel, Bruno, Ekeruche, Julia, Clement, Mathew, van den Berg, Hugo A., Price, David A., Sewell, Andrew K.
Publicado em 2010

Alterations in gap junction connexin43/connexin45 ratio mediate a transition from quiescence to excitation in a mathematical model of the myometrium

Por Sheldon, Rachel E., Mashayamombe, Chipo, Shi, Shao-Qing, Garfield, Robert E., Shmygol, Anatoly, Blanks, Andrew M., van den Berg, Hugo A.
Publicado no J R Soc Interface (2014)

Interaction between the CD8 Coreceptor and Major Histocompatibility Complex Class I Stabilizes T Cell Receptor-Antigen Complexes at the Cell Surface

Por Wooldridge, Linda, van den Berg, Hugo A., Glick, Meir, Gostick, Emma, Laugel, Bruno, Hutchinson, Sarah L., Milicic, Anita, Brenchley, Jason M., Douek, Daniel C., Price, David A., Sewell, Andrew K.
Publicado em 2005

Cellular-Level Versus Receptor-Level Response Threshold Hierarchies in T-Cell Activation

Por van den Berg, Hugo A., Ladell, Kristin, Miners, Kelly, Laugel, Bruno, Llewellyn-Lacey, Sian, Clement, Mathew, Cole, David K., Gostick, Emma, Wooldridge, Linda, Sewell, Andrew K., Bridgeman, John S., Price, David A.
Publicado em 2013

A Single Autoimmune T Cell Receptor Recognizes More Than a Million Different Peptides

Por Wooldridge, Linda, Ekeruche-Makinde, Julia, van den Berg, Hugo A., Skowera, Anna, Miles, John J., Tan, Mai Ping, Dolton, Garry, Clement, Mathew, Llewellyn-Lacey, Sian, Price, David A., Peakman, Mark, Sewell, Andrew K.
Publicado em 2012

Enhanced immunogenicity of CTL antigens through mutation of the CD8 binding MHC class I invariant region

Por Wooldridge, Linda, Lissina, Anna, Vernazza, Jonathan, Gostick, Emma, Laugel, Bruno, Hutchinson, Sarah L, Mirza, Fareed, Dunbar, P Rod, Boulter, Jonathan M, Glick, Meir, Cerundolo, Vincenzo, van den Berg, Hugo A, Price, David A, Sewell, Andrew K
Publicado em 2007

Avidity of influenza-specific memory CD8(+) T-cell populations decays over time compromising antiviral immunity

Por Humphreys, Ian R, Clement, Mathew, Marsden, Morgan, Ladell, Kristin, McLaren, James E, Smart, Kathryn, Hindley, James P, Bridgeman, Hayley M, van den Berg, Hugo A, Price, David A, Ager, Ann, Wooldridge, Linda, Godkin, Andrew, Gallimore, Awen M
Publicado em 2012

Protein kinase inhibitors substantially improve the physical detection of T-cells with peptide-MHC tetramers

Por Lissina, Anna, Ladell, Kristin, Skowera, Ania, Clement, Matthew, Edwards, Emily, Seggewiss, Ruth, van den Berg, Hugo A., Gostick, Emma, Gallagher, Kathleen, Jones, Emma, Melenhorst, J. Joseph, Godkin, Andrew J., Peakman, Mark, Price, David A., Sewell, Andrew K., Wooldridge, Linda
Publicado em 2009

Detection of low avidity CD8(+) T cell populations with coreceptor-enhanced peptide-major histocompatibility complex class I tetramers

Por Melenhorst, J. Joseph, Scheinberg, Phillip, Chattopadhyay, Pratip K., Lissina, Anna, Gostick, Emma, Cole, David K., Wooldridge, Linda, van den Berg, Hugo A., Bornstein, Ethan, Hensel, Nancy F., Douek, Daniel C., Roederer, Mario, Sewell, Andrew K., Barrett, A. John, Price, David A.
Publicado em 2008

Epitope Specificity Delimits the Functional Capabilities of Vaccine-Induced CD8 T Cell Populations

Por Hill, Brenna J., Darrah, Patricia A., Ende, Zachary, Ambrozak, David R., Quinn, Kylie M., Darko, Sam, Gostick, Emma, Wooldridge, Linda, van den Berg, Hugo A., Venturi, Vanessa, Larsen, Martin, Davenport, Miles P., Seder, Robert A., Price, David A., Douek, Daniel C.
Publicado no J Immunol (2014)

CD8(+) T-cell specificity is compromised at a defined MHCI/CD8 affinity threshold

Por Dockree, Tamsin, Holland, Christopher J, Clement, Mathew, Ladell, Kristin, McLaren, James E, van den Berg, Hugo A, Gostick, Emma, L Miners, Kelly, Llewellyn-Lacey, Sian, Bridgeman, John S, Man, Stephen, Bailey, Mick, Burrows, Scott R, Price, David A, Wooldridge, Linda
Publicado no Immunol Cell Biol (2017)

Identification of human viral protein-derived ligands recognized by individual MHCI-restricted T-cell receptors

Por Szomolay, Barbara, Liu, Jie, Brown, Paul E, Miles, John J, Clement, Mathew, Llewellyn-Lacey, Sian, Dolton, Garry, Ekeruche-Makinde, Julia, Lissina, Anya, Schauenburg, Andrea J, Sewell, Andrew K, Burrows, Scott R, Roederer, Mario, Price, David A, Wooldridge, Linda, van den Berg, Hugo A
Publicado no Immunol Cell Biol (2016)

Structural Mechanism Underpinning Cross-reactivity of a CD8(+) T-cell Clone That Recognizes a Peptide Derived from Human Telomerase Reverse Transcriptase

Por Cole, David K., van den Berg, Hugo A., Lloyd, Angharad, Crowther, Michael D., Beck, Konrad, Ekeruche-Makinde, Julia, Miles, John J., Bulek, Anna M., Dolton, Garry, Schauenburg, Andrea J., Wall, Aaron, Fuller, Anna, Clement, Mathew, Laugel, Bruno, Rizkallah, Pierre J., Wooldridge, Linda, Sewell, Andrew K.
Publicado no J Biol Chem (2017)

Targeted suppression of autoreactive CD8(+) T-cell activation using blocking anti-CD8 antibodies

Por Clement, Mathew, Pearson, James A., Gras, Stephanie, van den Berg, Hugo A., Lissina, Anya, Llewellyn-Lacey, Sian, Willis, Mark D., Dockree, Tamsin, McLaren, James E., Ekeruche-Makinde, Julia, Gostick, Emma, Robertson, Neil P., Rossjohn, Jamie, Burrows, Scott R., Price, David A., Wong, F. Susan, Peakman, Mark, Skowera, Ania, Wooldridge, Linda
Publicado no Sci Rep (2016)

Peptide length determines the outcome of TCR/peptide-MHCI engagement

Por Ekeruche-Makinde, Julia, Miles, John J., van den Berg, Hugo A., Skowera, Ania, Cole, David K., Dolton, Garry, Schauenburg, Andrea J. A., Tan, Mai Ping, Pentier, Johanne M., Llewellyn-Lacey, Sian, Miles, Kim M., Bulek, Anna M., Clement, Mathew, Williams, Tamsin, Trimby, Andrew, Bailey, Mick, Rizkallah, Pierre, Rossjohn, Jamie, Peakman, Mark, Price, David A., Burrows, Scott R., Sewell, Andrew K., Wooldridge, Linda
Publicado em 2013