Detection of low avidity CD8(+) T cell populations with coreceptor-enhanced peptide-major histocompatibility complex class I tetramers

The development of soluble recombinant peptide-major histocompatibility complex class I (pMHCI) molecules conjugated in multimeric form to fluorescent labels has enabled the physical quantification and characterization of antigen-specific CD8(+) T cell populations by flow cytometry. Several factors...

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Bibliografiska uppgifter
Huvudupphovsmän: Melenhorst, J. Joseph, Scheinberg, Phillip, Chattopadhyay, Pratip K., Lissina, Anna, Gostick, Emma, Cole, David K., Wooldridge, Linda, van den Berg, Hugo A., Bornstein, Ethan, Hensel, Nancy F., Douek, Daniel C., Roederer, Mario, Sewell, Andrew K., Barrett, A. John, Price, David A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714739/
https://ncbi.nlm.nih.gov/pubmed/18675271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2008.07.008
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