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Techniques to improve the direct ex vivo detection of low frequency antigen-specific CD8(+) T cells with peptide-major histocompatibility complex class I tetramers
The ability to quantify and characterize antigen-specific CD8(+) T cells irrespective of functional readouts using fluorochrome-conjugated tetrameric peptide-MHC class I (pMHCI) complexes in conjunction with flow cytometry has transformed our understanding of cellular immune responses over the past...
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| Autors principals: | , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2586006/ https://ncbi.nlm.nih.gov/pubmed/18836993 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cyto.a.20642 |
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