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High avidity myeloid leukemia-associated antigen-specific CD8(+) T cells preferentially reside in the bone marrow

The activity of allogeneic CD8(+) T cells specific for leukemia-associated antigens (LAAs) is thought to mediate, at least in part, the curative effects of hematopoietic stem cell transplantation (HSCT) in myeloid malignancies. However, the identity and nature of clinically relevant LAA-specific CD8...

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Autori principali: Melenhorst, J. Joseph, Scheinberg, Phillip, Chattopadhyay, Pratip K., Gostick, Emma, Ladell, Kristin, Roederer, Mario, Hensel, Nancy F., Douek, Daniel C., Barrett, A. John, Price, David A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652369/
https://ncbi.nlm.nih.gov/pubmed/18997173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-04-151969
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