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The cytolytic enzymes granyzme A, granzyme B, and perforin: expression patterns, cell distribution, and their relationship to cell maturity and bright CD57 expression

Cytolytic enzymes (CEs) are critical mediators of anti-viral and -tumor immunity; however, as a number of molecules belong to this enzyme family, our understanding of CEs remains limited. Specifically, it remains unclear what combinations of granzymes and perforin (Perf) are expressed by various imm...

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Main Authors: Chattopadhyay, Pratip K., Betts, Michael R., Price, David A., Gostick, Emma, Horton, Helen, Roederer, Mario, De Rosa, Stephen C.
格式: Artigo
語言:Inglês
出版: The Society for Leukocyte Biology 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2638730/
https://ncbi.nlm.nih.gov/pubmed/18820174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0208107
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