Superantigenic Yersinia pseudotuberculosis Induces the Expression of Granzymes and Perforin by CD4(+) T Cells

Bacterial superantigens (SAgs) are immunostimulatory toxins that induce acute diseases mainly through the massive release of inflammatory cytokines. Yersinia pseudotuberculosis is the only Gram-negative bacterium known to produce a SAg (Y. pseudotuberculosis-derived mitogen [YPM]). This SAg binds ma...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Goubard, Agathe, Loïez, Caroline, Abe, Jun, Fichel, Caroline, Herwegh, Stéphanie, Faveeuw, Christelle, Porte, Rémi, Cayet, Delphine, Sebbane, Florent, Penet, Sylvie, Foligné, Benoit, Desreumaux, Pierre, Saito, Hirohisa, Sirard, Jean-Claude, Simonet, Michel, Carnoy, Christophe
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Molecular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4399040/
https://ncbi.nlm.nih.gov/pubmed/25754199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02339-14
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