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The course of Mycobacterium tuberculosis infection in the lungs of mice lacking expression of either perforin- or granzyme-mediated cytolytic mechanisms.

CD8 T cells have been shown to be protective against Mycobacterium tuberculosis infections in the mouse. These cells have been shown to be cytolytic toward M. tuberculosis-infected cells and have also been shown to release the protective cytokine gamma interferon in response to mycobacterial antigen...

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Detalhes bibliográficos
Publicado no:Infect Immun
Principais autores: Cooper, A M, D'Souza, C, Frank, A A, Orme, I M
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175134/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9119468/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.65.4.1317-1320.1997
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