Cytolytic and ion channel-forming properties of the N terminus of lymphocyte perforin.

Perforin lyses cells by binding to the target cell membrane, where it polymerizes into large nonspecific pores. It is shown here that the first 34 amino acids of the N-terminal region of either human or murine perforin are soluble in aqueous medium and spontaneously insert into membranes. The N-term...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Ojcius, D M, Persechini, P M, Zheng, L M, Notaroberto, P C, Adeodato, S C, Young, J D
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1991
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC51717/
https://ncbi.nlm.nih.gov/pubmed/1711204
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