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Cognate peptides induce self-destruction of CD8+ cytolytic T lymphocytes.

Cytotoxic T lymphocytes (CTLs) have been shown to be relatively resistant to cytolytic attack by other CTLs. We show here, however, that cloned CTLs, in the absence of other cells, are destroyed by exposure to their cognate peptides (defined as those that in association with major histocompatibility...

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Detalhes bibliográficos
Main Authors: Walden, P R, Eisen, H N
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC55091/
https://ncbi.nlm.nih.gov/pubmed/2123347
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