Protein kinase inhibitors substantially improve the physical detection of T-cells with peptide-MHC tetramers

Flow cytometry with fluorochrome-conjugated peptide-major histocompatibility complex (pMHC) tetramers has transformed the study of antigen-specific T-cells by enabling their visualization, enumeration, phenotypic characterization and isolation from ex vivo samples. Here, we demonstrate that the reve...

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Main Authors: Lissina, Anna, Ladell, Kristin, Skowera, Ania, Clement, Matthew, Edwards, Emily, Seggewiss, Ruth, van den Berg, Hugo A., Gostick, Emma, Gallagher, Kathleen, Jones, Emma, Melenhorst, J. Joseph, Godkin, Andrew J., Peakman, Mark, Price, David A., Sewell, Andrew K., Wooldridge, Linda
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2009
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3052435/
https://ncbi.nlm.nih.gov/pubmed/18929568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2008.09.014
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