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Detection of low avidity CD8(+) T cell populations with coreceptor-enhanced peptide-major histocompatibility complex class I tetramers

The development of soluble recombinant peptide-major histocompatibility complex class I (pMHCI) molecules conjugated in multimeric form to fluorescent labels has enabled the physical quantification and characterization of antigen-specific CD8(+) T cell populations by flow cytometry. Several factors...

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Main Authors: Melenhorst, J. Joseph, Scheinberg, Phillip, Chattopadhyay, Pratip K., Lissina, Anna, Gostick, Emma, Cole, David K., Wooldridge, Linda, van den Berg, Hugo A., Bornstein, Ethan, Hensel, Nancy F., Douek, Daniel C., Roederer, Mario, Sewell, Andrew K., Barrett, A. John, Price, David A.
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714739/
https://ncbi.nlm.nih.gov/pubmed/18675271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2008.07.008
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