Bench, Bedside, Toolbox: T-Cells Deliver on Every Level

Por Laugel, Bruno
Publicado em 2014

Beyond the Antigen Receptor: Editing the Genome of T-Cells for Cancer Adoptive Cellular Therapies

Por Lloyd, Angharad, Vickery, Owen N., Laugel, Bruno
Publicado em 2013

Adenosine and cAMP signalling skew human dendritic cell differentiation towards a tolerogenic phenotype with defective CD8(+) T-cell priming capacity

Por Challier, John, Bruniquel, Denis, Sewell, Andrew K, Laugel, Bruno
Publicado em 2013

CD8 exerts differential effects on the deployment of cytotoxic T lymphocyte effector functions

Por Laugel, Bruno, Price, David A, Milicic, Anita, Sewell, Andrew K
Publicado em 2007

The molecular determinants of CD8 co-receptor function

Por Cole, David K, Laugel, Bruno, Clement, Mathew, Price, David A, Wooldridge, Linda, Sewell, Andrew K
Publicado em 2012

CD8 CONTROLS T CELL CROSSREACTIVITY

Por Wooldridge, Linda, Laugel, Bruno, Ekeruche, Julia, Clement, Mathew, van den Berg, Hugo A., Price, David A., Sewell, Andrew K.
Publicado em 2010

Functional and biophysical characterization of an HLA-A*6801-restricted HIV-specific T cell receptor

Por Gostick, Emma, Cole, David K, Hutchinson, Sarah L, Wooldridge, Linda, Tafuro, Sabrina, Laugel, Bruno, Lissina, Anna, Oxenius, Annette, Boulter, Jonathan M, Price, David A, Sewell, Andrew K
Publicado em 2007

Human TRAV1-2-negative MR1-restricted T cells detect S. pyogenes and alternatives to MAIT riboflavin-based antigens

Por Meermeier, Erin W., Laugel, Bruno F., Sewell, Andrew K., Corbett, Alexandra J., Rossjohn, Jamie, McCluskey, James, Harriff, Melanie J., Franks, Tamera, Gold, Marielle C., Lewinsohn, David M.
Publicado no Nat Commun (2016)

Interaction between the CD8 Coreceptor and Major Histocompatibility Complex Class I Stabilizes T Cell Receptor-Antigen Complexes at the Cell Surface

Por Wooldridge, Linda, van den Berg, Hugo A., Glick, Meir, Gostick, Emma, Laugel, Bruno, Hutchinson, Sarah L., Milicic, Anita, Brenchley, Jason M., Douek, Daniel C., Price, David A., Sewell, Andrew K.
Publicado em 2005

Engineering of Isogenic Cells Deficient for MR1 with a CRISPR/Cas9 Lentiviral System: Tools To Study Microbial Antigen Processing and Presentation to Human MR1-Restricted T Cells

Por Laugel, Bruno, Lloyd, Angharad, Meermeier, Erin W., Crowther, Michael D., Connor, Thomas R., Dolton, Garry, Miles, John J., Burrows, Scott R., Gold, Marielle C., Lewinsohn, David M., Sewell, Andrew K.
Publicado no J Immunol (2016)

Cellular-Level Versus Receptor-Level Response Threshold Hierarchies in T-Cell Activation

Por van den Berg, Hugo A., Ladell, Kristin, Miners, Kelly, Laugel, Bruno, Llewellyn-Lacey, Sian, Clement, Mathew, Cole, David K., Gostick, Emma, Wooldridge, Linda, Sewell, Andrew K., Bridgeman, John S., Price, David A.
Publicado em 2013

Enhanced immunogenicity of CTL antigens through mutation of the CD8 binding MHC class I invariant region

Por Wooldridge, Linda, Lissina, Anna, Vernazza, Jonathan, Gostick, Emma, Laugel, Bruno, Hutchinson, Sarah L, Mirza, Fareed, Dunbar, P Rod, Boulter, Jonathan M, Glick, Meir, Cerundolo, Vincenzo, van den Berg, Hugo A, Price, David A, Sewell, Andrew K
Publicado em 2007

Major histocompatibility complex class I molecules with super-enhanced CD8 binding properties bypass the requirement for cognate TCR recognition and non-specifically activate cytot...

Por Wooldridge, Linda, Clement, Matthew, Lissina, Anna, Edwards, Emily S. J., Ladell, Kristin, Ekeruche, Julia, Hewitt, Rachel E., Laugel, Bruno, Gostick, Emma, Cole, David K., Debets, Reno, Berrevoets, Cor, Miles, John J., Burrows, Scott R., Price, David A., Sewell, Andrew K.
Publicado em 2010

Structural Mechanism Underpinning Cross-reactivity of a CD8(+) T-cell Clone That Recognizes a Peptide Derived from Human Telomerase Reverse Transcriptase

Por Cole, David K., van den Berg, Hugo A., Lloyd, Angharad, Crowther, Michael D., Beck, Konrad, Ekeruche-Makinde, Julia, Miles, John J., Bulek, Anna M., Dolton, Garry, Schauenburg, Andrea J., Wall, Aaron, Fuller, Anna, Clement, Mathew, Laugel, Bruno, Rizkallah, Pierre J., Wooldridge, Linda, Sewell, Andrew K.
Publicado no J Biol Chem (2017)

Control of HIV-1 immune escape by CD8 T-cells expressing enhanced T-cell receptor

Por Varela-Rohena, Angel, Molloy, Peter E., Dunn, Steven M., Li, Yi, Suhoski, Megan M., Carroll, Richard G., Milicic, Anita, Mahon, Tara, Sutton, Deborah H., Laugel, Bruno E., Moysey, Ruth, Cameron, Brian J., Vuidepot, Annelise, Purbhoo, Marco E., Cole, David K., Phillips, Rodney E., June, Carl H., Jakobsen, Bent K., Sewell, Andrew K., Riley, James L.
Publicado em 2008

Peptide mimic for influenza vaccination using nonnatural combinatorial chemistry

Por Miles, John J., Tan, Mai Ping, Dolton, Garry, Edwards, Emily S.J., Galloway, Sarah A.E., Laugel, Bruno, Clement, Mathew, Makinde, Julia, Ladell, Kristin, Matthews, Katherine K., Watkins, Thomas S., Tungatt, Katie, Wong, Yide, Lee, Han Siean, Clark, Richard J., Pentier, Johanne M., Attaf, Meriem, Lissina, Anya, Ager, Ann, Gallimore, Awen, Rizkallah, Pierre J., Gras, Stephanie, Rossjohn, Jamie, Burrows, Scott R., Cole, David K., Price, David A., Sewell, Andrew K.
Publicado no J Clin Invest (2018)