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The molecular determinants of CD8 co-receptor function

CD8(+) T cells respond to signals mediated through a specific interaction between the T-cell receptor (TCR) and a composite antigen in the form of an epitopic peptide bound between the polymorphic α1 and α2 helices of an MHC class I (MHCI) molecule. The CD8 glycoprotein ‘co-receives’ antigen by bind...

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Detalhes bibliográficos
Main Authors: Cole, David K, Laugel, Bruno, Clement, Mathew, Price, David A, Wooldridge, Linda, Sewell, Andrew K
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461395/
https://ncbi.nlm.nih.gov/pubmed/22804746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2012.03625.x
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