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The molecular determinants of CD8 co-receptor function
CD8(+) T cells respond to signals mediated through a specific interaction between the T-cell receptor (TCR) and a composite antigen in the form of an epitopic peptide bound between the polymorphic α1 and α2 helices of an MHC class I (MHCI) molecule. The CD8 glycoprotein ‘co-receives’ antigen by bind...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Blackwell Science Inc
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3461395/ https://ncbi.nlm.nih.gov/pubmed/22804746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2012.03625.x |
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