Different affinity windows for virus and cancer-specific T-cell receptors – implications for therapeutic strategies

Por Aleksic, Milos, Liddy, Nathaniel, Molloy, Peter E, Pumphrey, Nick, Vuidepot, Annelise, Chang, Kyong-Mi, Jakobsen, Bent K
Publicado em 2012

ImmTACs: bi-specific TCR-anti-CD3 fusions for targeted tumour killing

Por Donnellan, Zoe, Bossi, Giovanna, Harper, Jane, Dukes, Joseph, Liddy, Nathaniel, Paston, Samantha, Mahon, Tara, Molloy, Peter, Sami, Malkit, Baston, Emma, Cameron, Brian, Johnson, Andrew, Vuidepot, Annelise, Hassan, Namir, Jakobsen, Bent
Publicado no J Immunother Cancer (2015)

Modulation of Hepatitis C Virus-Specific CD8 Effector T-Cell Function with Antiviral Effect in Infectious Hepatitis C Virus Coculture Model

Por Ojiro, Keisuke, Qu, Xiaowang, Cho, Hyosun, Park, Jang-June, Vuidepot, Annelise, Lissin, Nikolai, Molloy, Peter E., Bennett, Alan, Jakobsen, Bent K., Kaplan, David E., Riley, James L., Chang, Kyong-Mi
Publicado no J Virol (2017)

TCR affinity and specificity requirements for human regulatory T-cell function

Por Plesa, Gabriela, Zheng, Lingjie, Medvec, Andrew, Wilson, Caleph B., Robles-Oteiza, Camila, Liddy, Nathaniel, Bennett, Alan D., Gavarret, Jessie, Vuidepot, Annelise, Zhao, Yangbing, Blazar, Bruce R., Jakobsen, Bent K., Riley, James L.
Publicado em 2012

Crystallization and preliminary X-ray structural studies of a Melan-A pMHC–TCR complex

Por Yuan, Fang, Georgiou, Theonie, Hillon, Theresa, Gostick, Emma, Price, David A., Sewell, Andrew K., Moysey, Ruth, Gavarret, Jessie, Vuidepot, Annelise, Sami, Malkit, Bell, John I., Gao, George F., Rizkallah, Pierre J., Jakobsen, Bent K.
Publicado em 2007

Elimination of Latently HIV-infected Cells from Antiretroviral Therapy-suppressed Subjects by Engineered Immune-mobilizing T-cell Receptors

Por Yang, Hongbing, Buisson, Sandrine, Bossi, Giovanna, Wallace, Zoë, Hancock, Gemma, So, Chun, Ashfield, Rebecca, Vuidepot, Annelise, Mahon, Tara, Molloy, Peter, Oates, Joanne, Paston, Samantha J, Aleksic, Milos, Hassan, Namir J, Jakobsen, Bent K, Dorrell, Lucy
Publicado no Mol Ther (2016)

Cancer-specific T cell receptor isolation for cancer immunotherapy

Por Baker, Debbie Emma, Hibbert, Linda, Weigand, Luise, Paston, Samantha, Ryan, Ruth, Donnellan, Zoe, Simmons, Ruth, Hale, Kathy, Conlon, Louise, Dukes, Joseph, Clark, Vanessa, Boudousquie, Caroline, Bossi, Giovanna, Hickman, Emma, Powlesland, Alex, Vuidepot, Annelise, Hassan, Namir, Jakobsen, Bent
Publicado no J Immunother Cancer (2015)

Direct molecular mimicry enables off-target cardiovascular toxicity by an enhanced affinity TCR designed for cancer immunotherapy

Por Raman, Marine C C, Rizkallah, Pierre J, Simmons, Ruth, Donnellan, Zoe, Dukes, Joseph, Bossi, Giovanna, Le Provost, Gabrielle S, Todorov, Penio, Baston, Emma, Hickman, Emma, Mahon, Tara, Hassan, Namir, Vuidepot, Annelise, Sami, Malkit, Cole, David K, Jakobsen, Bent K.
Publicado no Sci Rep (2016)

Bi-specific TCR-anti CD3 redirected T-cell targeting of NY-ESO-1- and LAGE-1-positive tumors

Por McCormack, Emmet, Adams, Katherine J., Hassan, Namir J., Kotian, Akhil, Lissin, Nikolai M., Sami, Malkit, Mujić, Maja, Osdal, Tereza, Gjertsen, Bjørn Tore, Baker, Deborah, Powlesland, Alex S., Aleksic, Milos, Vuidepot, Annelise, Morteau, Olivier, Sutton, Deborah H., June, Carl H., Kalos, Michael, Ashfield, Rebecca, Jakobsen, Bent K.
Publicado em 2012

High affinity soluble ILT2 receptor: a potent inhibitor of CD8(+) T cell activation

Por Moysey, Ruth K., Li, Yi, Paston, Samantha J., Baston, Emma E., Sami, Malkit S., Cameron, Brian J., Gavarret, Jessie, Todorov, Penio, Vuidepot, Annelise, Dunn, Steven M., Pumphrey, Nicholas J., Adams, Katherine J., Yuan, Fang, Dennis, Rebecca E., Sutton, Deborah H., Johnson, Andy D., Brewer, Joanna E., Ashfield, Rebecca, Lissin, Nikolai M., Jakobsen, Bent K.
Publicado no Protein Cell (2011)

Control of HIV-1 immune escape by CD8 T-cells expressing enhanced T-cell receptor

Por Varela-Rohena, Angel, Molloy, Peter E., Dunn, Steven M., Li, Yi, Suhoski, Megan M., Carroll, Richard G., Milicic, Anita, Mahon, Tara, Sutton, Deborah H., Laugel, Bruno E., Moysey, Ruth, Cameron, Brian J., Vuidepot, Annelise, Purbhoo, Marco E., Cole, David K., Phillips, Rodney E., June, Carl H., Jakobsen, Bent K., Sewell, Andrew K., Riley, James L.
Publicado em 2008