Vaccination against the Intracellular Pathogens Leishmania major and L. amazonensis by Directing CD40 Ligand to Macrophages

Por Chen, Gang, Darrah, Patricia A., Mosser, David M.
Publicado em 2001

The Regulation of Th1 Responses by the p38 MAPK

Por Yang, Ziyan, Zhang, Xia, Darrah, Patricia A., Mosser, David M.
Publicado em 2010

Cooperation between Reactive Oxygen and Nitrogen Intermediates in Killing of Rhodococcus equi by Activated Macrophages

Por Darrah, Patricia A., Hondalus, Mary K., Chen, Quiping, Ischiropoulos, Harry, Mosser, David M.
Publicado em 2000

IL-10 production differentially influences the magnitude, quality, and protective capacity of Th1 responses depending on the vaccine platform

Por Darrah, Patricia A., Hegde, Sonia T., Patel, Dipti T., Lindsay, Ross W. B., Chen, Linda, Roederer, Mario, Seder, Robert A.
Publicado em 2010

Pathogen-Specific T Cell Polyfunctionality Is a Correlate of T Cell Efficacy and Immune Protection

Por Boyd, Anders, Almeida, Jorge R., Darrah, Patricia A., Sauce, Delphine, Seder, Robert A., Appay, Victor, Gorochov, Guy, Larsen, Martin
Publicado no PLoS One (2015)

Correction: Pathogen-Specific T Cell Polyfunctionality Is a Correlate of T Cell Efficacy and Immune Protection

Por Boyd, Anders, Almeida, Jorge R., Darrah, Patricia A., Sauce, Delphine, Seder, Robert A., Appay, Victor, Gorochov, Guy, Larsen, Martin
Publicado no PLoS One (2015)

Dendritic Cells Are Responsible for the Capacity of CpG Oligodeoxynucleotides to Act as an Adjuvant for Protective Vaccine Immunity Against Leishmania major in Mice

Por Shah, Javeed A., Darrah, Patricia A., Ambrozak, David R., Turon, Tara N., Mendez, Susana, Kirman, Joanna, Wu, Chang-You, Glaichenhaus, Nicolas, Seder, Robert A.
Publicado em 2003

Toward Tuberculosis Vaccine Development: Recommendations for Nonhuman Primate Study Design

Por Laddy, Dominick J., Bonavia, Aurelio, Hanekom, Willem A., Kaushal, Deepak, Williams, Ann, Roederer, Mario, Seder, Robert A., Sharpe, Sally, Verreck, Frank A. W., Darrah, Patricia A.
Publicado no Infect Immun (2018)

Monocytes Acquire the Ability to Prime Tissue-Resident T Cells via IL-10-Mediated TGF-β Release

Por Thompson, Elizabeth A., Darrah, Patricia A., Foulds, Kathryn E., Hoffer, Elena, Caffrey-Carr, Alayna, Norenstedt, Sophie, Perbeck, Leif, Seder, Robert A., Kedl, Ross M., Loré, Karin
Publicado no Cell Rep (2019)

Co-Administration of Poly I:C and ISCOMs Modifies Antigen Processing in Dendritic Cell Subsets and Enhances HIV Gag-Specific T Cell Immunity

Por Quinn, Kylie M., Yamamoto, Ayako, Costa, Andreia, Darrah, Patricia A., Lindsay, Ross W.B., Hegde, Sonia T., Johnson, Teresa R., Flynn, Barbara J., Lore, Karin, Seder, Robert A.
Publicado em 2013

Human Anti-CD40 Antibody and Poly IC:LC Adjuvant Combination Induces Potent T Cell Responses in the Lung of Non-Human Primates()

Por Thompson, Elizabeth A, Liang, Frank, Lindgren, Gustaf, Sandgren, Kerrie J, Quinn, Kylie M, Darrah, Patricia A, Koup, Richard A, Seder, Robert A, Kedl, Ross M, Loré, Karin
Publicado no J Immunol (2015)

SIV infection of rhesus macaques results in dysfunctional T- and B-cell responses to neo and recall Leishmania major vaccination

Por Klatt, Nichole R., Vinton, Carol L., Lynch, Rebecca M., Canary, Lauren A., Ho, Jason, Darrah, Patricia A., Estes, Jacob D., Seder, Robert A., Moir, Susan L., Brenchley, Jason M.
Publicado em 2011

T Cells Specific for a Mycobacterial Glycolipid Expand after Intravenous Bacillus Calmette–Guérin Vaccination

Por Layton, Erik D., Barman, Soumik, Wilburn, Damien B., Yu, Krystle K. Q., Smith, Malisa T., Altman, John D., Scriba, Thomas J., Tahiri, Nabil, Minnaard, Adriaan J., Roederer, Mario, Seder, Robert A., Darrah, Patricia A., Seshadri, Chetan
Publicado no J Immunol (2021)

Conservation of molecular and cellular phenotypes of invariant NKT cells between humans and non-human primates

Por Yu, Krystle K. Q., Wilburn, Damien B., Hackney, Joshua A., Darrah, Patricia A., Foulds, Kathryn E., James, Charlotte A., Smith, Malisa T., Jing, Lichen, Seder, Robert A., Roederer, Mario, Koelle, David M., Swanson, Willie J., Seshadri, Chetan
Publicado no Immunogenetics (2019)

A nonhuman primate toxicology and immunogenicity study evaluating aerosol delivery of AERAS-402/Ad35 vaccine: Evidence for transient t cell responses in peripheral blood and robust...

Por Hokey, David A, Wachholder, Robert, Darrah, Patricia A, Bolton, Diane L, Barouch, Dan H, Hill, Krystal, Dheenadhayalan, Veerabadran, Schwander, Stephan, Godin, C Steven, Douoguih, Macaya, Pau, Maria Grazia, Seder, Robert A, Roederer, Mario, Sadoff, Jerald C, Sizemore, Donata
Publicado no Hum Vaccin Immunother (2014)

Protective T cell immunity in mice following protein-TLR7/8 agonist-conjugate immunization requires aggregation, type I IFN, and multiple DC subsets

Por Kastenmüller, Kathrin, Wille-Reece, Ulrike, Lindsay, Ross W.B., Trager, Lauren R., Darrah, Patricia A., Flynn, Barbara J., Becker, Maria R., Udey, Mark C., Clausen, Björn E., Igyarto, Botond Z., Kaplan, Daniel H., Kastenmüller, Wolfgang, Germain, Ronald N., Seder, Robert A.
Publicado em 2011

Epitope Specificity Delimits the Functional Capabilities of Vaccine-Induced CD8 T Cell Populations

Por Hill, Brenna J., Darrah, Patricia A., Ende, Zachary, Ambrozak, David R., Quinn, Kylie M., Darko, Sam, Gostick, Emma, Wooldridge, Linda, van den Berg, Hugo A., Venturi, Vanessa, Larsen, Martin, Davenport, Miles P., Seder, Robert A., Price, David A., Douek, Daniel C.
Publicado no J Immunol (2014)

Aerosol Vaccination with AERAS-402 Elicits Robust Cellular Immune Responses in the Lungs of Rhesus Macaques but Fails to Protect Against High-Dose Mycobacterium tuberculosis Challe...

Por Darrah, Patricia A., Bolton, Diane L., Lackner, Andrew A., Kaushal, Deepak, Aye, Pyone Pyone, Mehra, Smriti, Blanchard, James L., Didier, Peter J., Roy, Chad J., Rao, Srinivas S., Hokey, David A., Scanga, Charles A., Sizemore, Donata R., Sadoff, Jerald C., Roederer, Mario, Seder, Robert A.
Publicado em 2014

Boosting BCG with proteins or rAd5 does not enhance protection against tuberculosis in rhesus macaques

Por Darrah, Patricia A., DiFazio, Robert M., Maiello, Pauline, Gideon, Hannah P., Myers, Amy J., Rodgers, Mark A., Hackney, Joshua A., Lindenstrom, Thomas, Evans, Thomas, Scanga, Charles A., Prikhodko, Victor, Andersen, Peter, Lin, Philana Ling, Laddy, Dominick, Roederer, Mario, Seder, Robert A., Flynn, JoAnne L.
Publicado no NPJ Vaccines (2019)

Antigen expression determines adenoviral vaccine potency independent of IFN and STING signaling

Por Quinn, Kylie M., Zak, Daniel E., Costa, Andreia, Yamamoto, Ayako, Kastenmuller, Kathrin, Hill, Brenna J., Lynn, Geoffrey M., Darrah, Patricia A., Lindsay, Ross W.B., Wang, Lingshu, Cheng, Cheng, Nicosia, Alfredo, Folgori, Antonella, Colloca, Stefano, Cortese, Riccardo, Gostick, Emma, Price, David A., Gall, Jason G.D., Roederer, Mario, Aderem, Alan, Seder, Robert A.
Publicado no J Clin Invest (2015)