Co-Administration of Poly I:C and ISCOMs Modifies Antigen Processing in Dendritic Cell Subsets and Enhances HIV Gag-Specific T Cell Immunity

Currently approved adjuvants induce protective antibody responses but are more limited for generating cellular immunity. Here we assessed the effect of combining two adjuvants with distinct mechanisms of action on their ability to prime T cells; the TLR3 ligand, polyinosinic:polycytidylic acid (Poly...

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Autors principals: Quinn, Kylie M., Yamamoto, Ayako, Costa, Andreia, Darrah, Patricia A., Lindsay, Ross W.B., Hegde, Sonia T., Johnson, Teresa R., Flynn, Barbara J., Lore, Karin, Seder, Robert A.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4100557/
https://ncbi.nlm.nih.gov/pubmed/24089189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301730
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