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Co-Administration of Poly I:C and ISCOMs Modifies Antigen Processing in Dendritic Cell Subsets and Enhances HIV Gag-Specific T Cell Immunity

Currently approved adjuvants induce protective antibody responses but are more limited for generating cellular immunity. Here we assessed the effect of combining two adjuvants with distinct mechanisms of action on their ability to prime T cells; the TLR3 ligand, polyinosinic:polycytidylic acid (Poly...

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Main Authors: Quinn, Kylie M., Yamamoto, Ayako, Costa, Andreia, Darrah, Patricia A., Lindsay, Ross W.B., Hegde, Sonia T., Johnson, Teresa R., Flynn, Barbara J., Lore, Karin, Seder, Robert A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4100557/
https://ncbi.nlm.nih.gov/pubmed/24089189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301730
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