Human Anti-CD40 Antibody and Poly IC:LC Adjuvant Combination Induces Potent T Cell Responses in the Lung of Non-Human Primates()

Non-live vaccine platforms that induce potent cellular immune responses in mucosal tissue would have broad application for vaccines against infectious diseases and tumors. Induction of cellular immunity could be optimized by targeted activation of multiple innate and co-stimulatory signaling pathway...

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Udgivet i:J Immunol
Main Authors: Thompson, Elizabeth A, Liang, Frank, Lindgren, Gustaf, Sandgren, Kerrie J, Quinn, Kylie M, Darrah, Patricia A, Koup, Richard A, Seder, Robert A, Kedl, Ross M, Loré, Karin
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4506869/
https://ncbi.nlm.nih.gov/pubmed/26123354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500078
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