POLY IC IS THE MOST EFFECTIVE TOLL-LIKE RECEPTOR ADJUVANT FOR SIV GAG PROTEIN INDUCED T CELL RESPONSES IN NON-HUMAN PRIMATES

Prime-boost immunization with heterologous vaccines elicits potent cellular immunity. Here, we assessed the influence of various TLR ligands on SIV Gag-specific T cell immunity and protection following prime-boost immunization. Rhesus macaques (RM) were primed with SIV Gag protein emulsified in mont...

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Main Authors: Park, Haesun, Adamson, Lauren, Ha, Tae, Mullen, Karl, Hagen, Shoko I, Nogueron, Arys, Sylwester, Andrew W., Axthelm, Michael K., Legasse, Al, Piatak, Michael, Lifson, Jeffrey D., McElrath, Juliana M., Picker, Louis J., Seder, Robert A.
格式: Artigo
語言:Inglês
出版: 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622154/
https://ncbi.nlm.nih.gov/pubmed/23509365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202958
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