A B cell follicle sanctuary permits persistent productive SIV infection in elite controllers

Chronic phase HIV/SIV replication is reduced by as much as 10,000-fold in elite controllers (EC) compared to typical progressors, but sufficient viral replication persists in EC tissues to allow viral sequence evolution and induce excess immune activation. Here, we show that productive SIV infection...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Med
Main Authors: Fukazawa, Yoshinori, Lum, Richard, Okoye, Afam A., Park, Haesun, Matsuda, Kenta, Bae, Jin Young, Hagen, Shoko I., Shoemaker, Rebecca, Deleage, Claire, Lucero, Carissa, Morcock, David, Swanson, Tonya, Legasse, Alfred W., Axthelm, Michael K., Hesselgesser, Joseph, Geleziunas, Romas, Hirsch, Vanessa M., Edlefsen, Paul T., Piatak, Michael, Estes, Jacob D., Lifson, Jeffrey D., Picker, Louis J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4320022/
https://ncbi.nlm.nih.gov/pubmed/25599132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3781
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados