Increased CD4+ T cell levels during IL-7 administration of ART treated SIV+ macaques are not dependent on strong proliferative responses

CD4+ T cell depletion is a fundamental component of HIV infection and AIDS pathogenesis, and is not always reversed following anti-retroviral therapy (ART). Here the SIV-infected Rhesus macaque model was utilized to assess recombinant simian IL-7 in its glycosylated form (rsIL-7gly) to enhance regen...

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Bibliografiska uppgifter
Huvudupphovsmän: Leone, Amanda, Rohankhedkhar, Mukta, Okoye, Afam, Legasse, Alfred, Axthelm, Michael K., Villinger, Francois, Piatak, Michael, Lifson, Jeffrey D., Assouline, Brigitte, Morre, Michel, Picker, Louis J., Sodora, Donald L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3050806/
https://ncbi.nlm.nih.gov/pubmed/20622118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902626
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