Naive T cells are dispensable for memory CD4(+) T cell homeostasis in progressive simian immunodeficiency virus infection

The development of AIDS in chronic HIV/simian immunodeficiency virus (SIV) infection has been closely linked to progressive failure of CD4(+) memory T cell (T(M)) homeostasis. CD4(+) naive T cells (T(N)) also decline in these infections, but their contribution to disease progression is less clear. W...

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Hlavní autoři: Okoye, Afam A., Rohankhedkar, Mukta, Abana, Chike, Pattenn, Audrie, Reyes, Matthew, Pexton, Christopher, Lum, Richard, Sylwester, Andrew, Planer, Shannon L., Legasse, Alfred, Park, Byung S., Piatak, Michael, Lifson, Jeffrey D., Axthelm, Michael K., Picker, Louis J.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2012
Témata:
Brief Definitive Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328373/
https://ncbi.nlm.nih.gov/pubmed/22451717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20112071
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