Lymph node T cell responses predict the efficacy of live attenuated SIV vaccines

Live attenuated SIV vaccines (LAVs) remain the most efficacious of all vaccines in nonhuman primate (NHP) models of HIV/AIDS, yet the basis of their robust protection remains poorly understood. Here, we demonstrate that the degree of LAV-mediated protection against intravenous wildtype SIVmac239 cha...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Fukazawa, Yoshinori, Park, Haesun, Cameron, Mark J., Lefebvre, Francois, Lum, Richard, Coombes, Noel, Mahyari, Eisa, Hagen, Shoko, Bae, Jin Young, Reyes, Marcelo Delos, Swanson, Tonya, Legasse, Alfred W., Sylwester, Andrew, Hansen, Scott G., Smith, Andrew T., Stafova, Petra, Shoemaker, Rebecca, Li, Yuan, Oswald, Kelli, Axthelm, Michael K., McDermott, Adrian, Ferrari, Guido, Montefiori, David C., Edlefsen, Paul T., Piatak, Michael, Lifson, Jeffrey D., Sékaly, Rafick P., Picker, Louis J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493820/
https://ncbi.nlm.nih.gov/pubmed/22961108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2934
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