Profound early control of highly pathogenic SIV by an effector-memory T cell vaccine

The AIDS-causing lentiviruses HIV and SIV effectively evade host immunity, and once established, infections with these viruses are only rarely controlled by immunologic mechanisms(1-3). However, the initial establishment of infection in the first few days after mucosal exposure, prior to viral disse...

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Auteurs principaux: Hansen, Scott G., Ford, Julia C., Lewis, Matthew S., Ventura, Abigail B., Hughes, Colette M., Coyne-Johnson, Lia, Whizin, Nathan, Oswald, Kelli, Shoemaker, Rebecca, Swanson, Tonya, Legasse, Alfred W., Chiuchiolo, Maria J., Parks, Christopher L., Axthelm, Michael K., Nelson, Jay A., Jarvis, Michael A., Piatak, Michael, Lifson, Jeffrey D., Picker, Louis J.
Format: Artigo
Langue:Inglês
Publié: 2011
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102768/
https://ncbi.nlm.nih.gov/pubmed/21562493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10003
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