Effector-memory T cell responses are associated with protection of rhesus monkeys from mucosal SIV challenge

The rapid onset of massive, systemic viral replication during primary HIV/SIV infection and the immune evasion capabilities of these viruses pose fundamental problems for vaccines that depend upon initial viral replication to stimulate effector T cell expansion and differentiation1–5. We hypothesize...

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Detalhes bibliográficos
Main Authors: Hansen, Scott G., Vieville, Cassandra, Whizin, Nathan, Coyne-Johnson, Lia, Siess, Don C., Drummond, Derek D., Legasse, Alfred W., Axthelm, Michael K., Oswald, Kelli, Trubey, Charles M., Piatak, Michael, Lifson, Jeffrey D., Nelson, Jay A., Jarvis, Michael A., Picker, Louis J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720091/
https://ncbi.nlm.nih.gov/pubmed/19219024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.1935
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