Rapid Inflammasome Activation Following Mucosal SIV Infection of Rhesus Monkeys

The earliest events following mucosal HIV-1 infection, prior to measurable viremia, remain poorly understood. Here we show by detailed necropsy studies that the virus can disseminate rapidly following mucosal SIV infection of rhesus monkeys and trigger components of the inflammasome, both at the sit...

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Publicado no:Cell
Main Authors: Barouch, Dan H., Ghneim, Khader, Bosche, William J., Li, Yuan, Berkemeier, Brian, Hull, Michael, Bhattacharyya, Sanghamitra, Cameron, Mark, Liu, Jinyan, Smith, Kaitlin, Borducchi, Erica, Cabral, Crystal, Peter, Lauren, Brinkman, Amanda, Shetty, Mayuri, Li, Hualin, Gittens, Courtney, Baker, Chantelle, Wagner, Wendeline, Lewis, Mark G., Colantonio, Arnaud, Kang, Hyung-Joo, Li, Wenjun, Lifson, Jeffrey D., Piatak, Michael, Sekaly, Rafick-Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4842119/
https://ncbi.nlm.nih.gov/pubmed/27085913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.03.021
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