Rapid Seeding of the Viral Reservoir Prior to SIV Viremia in Rhesus Monkeys

The viral reservoir represents a critical challenge facing HIV-1 eradication strategies(1–5). However, it remains unclear when and where the viral reservoir is seeded during acute infection and the extent to which it is susceptible to early antiretroviral therapy (ART). Here we show that the viral r...

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Main Authors: Whitney, James B., Hill, Alison L., Sanisetty, Srisowmya, Penaloza-MacMaster, Pablo, Liu, Jinyan, Shetty, Mayuri, Parenteau, Lily, Cabral, Crystal, Shields, Jennifer, Blackmore, Stephen, Smith, Jeffrey Y., Brinkman, Amanda L., Peter, Lauren E., Mathew, Sheeba I., Smith, Kaitlin M., Borducchi, Erica N., Rosenbloom, Daniel I.S., Lewis, Mark G., Hattersley, Jillian, Li, Bei, Hesselgesser, Joseph, Geleziunas, Romas, Robb, Merlin L., Kim, Jerome H., Michael, Nelson L., Barouch, Dan H.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4126858/
https://ncbi.nlm.nih.gov/pubmed/25042999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13594
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