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Origin of rebound virus in chronically SIV-infected Rhesus monkeys following treatment discontinuation

Viral rebound following antiretroviral therapy (ART) discontinuation in HIV-1-infected individuals is believed to originate from a small pool of CD4+ T cells harboring replication-competent provirus. However, the origin and nature of the rebound virus has remained unclear. Recent studies have sugges...

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Foilsithe in:Nat Commun
Main Authors: Liu, Po-Ting, Keele, Brandon F., Abbink, Peter, Mercado, Noe B., Liu, Jinyan, Bondzie, Esther A., Chandrashekar, Abishek, Borducchi, Erica N., Hesselgesser, Joseph, Mish, Michael, Chin, Gregory, Bekerman, Elena, Geleziunas, Romas, Barouch, Dan H.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7591481/
https://ncbi.nlm.nih.gov/pubmed/33110078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19254-2
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