Origin of rebound virus in chronically SIV-infected Rhesus monkeys following treatment discontinuation

Viral rebound following antiretroviral therapy (ART) discontinuation in HIV-1-infected individuals is believed to originate from a small pool of CD4+ T cells harboring replication-competent provirus. However, the origin and nature of the rebound virus has remained unclear. Recent studies have sugges...

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Publié dans:Nat Commun
Auteurs principaux: Liu, Po-Ting, Keele, Brandon F., Abbink, Peter, Mercado, Noe B., Liu, Jinyan, Bondzie, Esther A., Chandrashekar, Abishek, Borducchi, Erica N., Hesselgesser, Joseph, Mish, Michael, Chin, Gregory, Bekerman, Elena, Geleziunas, Romas, Barouch, Dan H.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7591481/
https://ncbi.nlm.nih.gov/pubmed/33110078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19254-2
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