Origin of rebound virus in chronically SIV-infected Rhesus monkeys following treatment discontinuation

Viral rebound following antiretroviral therapy (ART) discontinuation in HIV-1-infected individuals is believed to originate from a small pool of CD4+ T cells harboring replication-competent provirus. However, the origin and nature of the rebound virus has remained unclear. Recent studies have sugges...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Liu, Po-Ting, Keele, Brandon F., Abbink, Peter, Mercado, Noe B., Liu, Jinyan, Bondzie, Esther A., Chandrashekar, Abishek, Borducchi, Erica N., Hesselgesser, Joseph, Mish, Michael, Chin, Gregory, Bekerman, Elena, Geleziunas, Romas, Barouch, Dan H.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7591481/
https://ncbi.nlm.nih.gov/pubmed/33110078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19254-2
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