Rapid Inflammasome Activation Following Mucosal SIV Infection of Rhesus Monkeys

The earliest events following mucosal HIV-1 infection, prior to measurable viremia, remain poorly understood. Here we show by detailed necropsy studies that the virus can disseminate rapidly following mucosal SIV infection of rhesus monkeys and trigger components of the inflammasome, both at the sit...

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Bibliografiska uppgifter
I publikationen:Cell
Huvudupphovsmän: Barouch, Dan H., Ghneim, Khader, Bosche, William J., Li, Yuan, Berkemeier, Brian, Hull, Michael, Bhattacharyya, Sanghamitra, Cameron, Mark, Liu, Jinyan, Smith, Kaitlin, Borducchi, Erica, Cabral, Crystal, Peter, Lauren, Brinkman, Amanda, Shetty, Mayuri, Li, Hualin, Gittens, Courtney, Baker, Chantelle, Wagner, Wendeline, Lewis, Mark G., Colantonio, Arnaud, Kang, Hyung-Joo, Li, Wenjun, Lifson, Jeffrey D., Piatak, Michael, Sekaly, Rafick-Pierre
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4842119/
https://ncbi.nlm.nih.gov/pubmed/27085913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.03.021
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