A live-attenuated RhCMV/SIV vaccine shows long-term efficacy against heterologous SIV challenge

Previous studies have established that strain 68–1-derived Rhesus cytomegalovirus (RhCMV) vectors expressing simian immune deficiency virus (SIV) proteins (RhCMV/SIV) are able to elicit and maintain cellular immune responses that provide protection against mucosal challenge with highly pathogenic SI...

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Xehetasun bibliografikoak
Argitaratua izan da:Sci Transl Med
Egile Nagusiak: Hansen, Scott G., Marshall, Emily E., Malouli, Daniel, Ventura, Abigail B., Hughes, Colette M., Ainslie, Emily, Ford, Julia C., Morrow, David, Gilbride, Roxanne M., Bae, Jin Y., Legasse, Alfred W., Oswald, Kelli, Shoemaker, Rebecca, Berkemeier, Brian, Bosche, William J., Hull, Michael, Womack, Jennie, Shao, Jason, Edlefsen, Paul T., Reed, Jason S., Burwitz, Ben J., Sacha, Jonah B., Axthelm, Michael K., Früh, Klaus, Lifson, Jeffrey D., Picker, Louis J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6788755/
https://ncbi.nlm.nih.gov/pubmed/31316007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaw2607
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