Cytomegaloviral Determinants of CD8(+) T Cell Programming and RhCMV/SIV Vaccine Efficacy

Simian immunodeficiency virus (SIV) insert-expressing, 68–1 Rhesus Cytomegalovirus (RhCMV/SIV) vectors elicit major histocompatibility complex (MHC)-E- and -II-restricted, SIV-specific CD8(+) T cell responses, but the basis of these unconventional responses and their contribution to demonstrated vac...

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Pubblicato in:Sci Immunol
Autori principali: Malouli, Daniel, Hansen, Scott G., Hancock, Meaghan H., Hughes, Colette M., Ford, Julia C., Gilbride, Roxanne M., Ventura, Abigail B., Morrow, David, Randall, Kurt T., Taher, Husam, Uebelhoer, Luke S., McArdle, Matthew R., Papen, Courtney R., Trethewy, Renee Espinosa, Oswald, Kelli, Shoemaker, Rebecca, Berkemeier, Brian, Bosche, William J., Hull, Michael, Greene, Justin M., Axthelm, Michael K., Shao, Jason, Edlefsen, Paul T., Grey, Finn, Nelson, Jay A., Lifson, Jeffrey D., Streblow, Daniel, Sacha, Jonah B., Früh, Klaus, Picker, Louis J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8244349/
https://ncbi.nlm.nih.gov/pubmed/33766849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.abg5413
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