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Interleukin-15 response signature predicts RhCMV/SIV vaccine efficacy

Simian immunodeficiency virus (SIV) challenge of rhesus macaques (RMs) vaccinated with strain 68–1 Rhesus Cytomegalovirus (RhCMV) vectors expressing SIV proteins (RhCMV/SIV) results in a binary outcome: stringent control and subsequent clearance of highly pathogenic SIV in ~55% of vaccinated RMs wit...

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書誌詳細
出版年:PLoS Pathog
主要な著者: Barrenäs, Fredrik, Hansen, Scott G., Law, Lynn, Driscoll, Connor, Green, Richard R., Smith, Elise, Chang, Jean, Golez, Inah, Urion, Taryn, Peng, Xinxia, Whitmore, Leanne, Newhouse, Daniel, Hughes, Colette M., Morrow, David, Randall, Kurt T., Selseth, Andrea N., Ford, Julia C., Gilbride, Roxanne M., Randall, Bryan E., Ainslie, Emily, Oswald, Kelli, Shoemaker, Rebecca, Fast, Randy, Bosche, William J., Axthelm, Michael K., Fukazawa, Yoshinori, Pavlakis, George N., Felber, Barbara K., Fourati, Slim, Sekaly, Rafick-Pierre, Lifson, Jeffrey D., Komorowski, Jan, Kosmider, Ewelina, Shao, Danica, Song, Wenjun, Edlefsen, Paul T., Picker, Louis J., Gale, Michael
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8284654/
https://ncbi.nlm.nih.gov/pubmed/34228762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009278
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