Interleukin-15 response signature predicts RhCMV/SIV vaccine efficacy

Simian immunodeficiency virus (SIV) challenge of rhesus macaques (RMs) vaccinated with strain 68–1 Rhesus Cytomegalovirus (RhCMV) vectors expressing SIV proteins (RhCMV/SIV) results in a binary outcome: stringent control and subsequent clearance of highly pathogenic SIV in ~55% of vaccinated RMs wit...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:PLoS Pathog
المؤلفون الرئيسيون: Barrenäs, Fredrik, Hansen, Scott G., Law, Lynn, Driscoll, Connor, Green, Richard R., Smith, Elise, Chang, Jean, Golez, Inah, Urion, Taryn, Peng, Xinxia, Whitmore, Leanne, Newhouse, Daniel, Hughes, Colette M., Morrow, David, Randall, Kurt T., Selseth, Andrea N., Ford, Julia C., Gilbride, Roxanne M., Randall, Bryan E., Ainslie, Emily, Oswald, Kelli, Shoemaker, Rebecca, Fast, Randy, Bosche, William J., Axthelm, Michael K., Fukazawa, Yoshinori, Pavlakis, George N., Felber, Barbara K., Fourati, Slim, Sekaly, Rafick-Pierre, Lifson, Jeffrey D., Komorowski, Jan, Kosmider, Ewelina, Shao, Danica, Song, Wenjun, Edlefsen, Paul T., Picker, Louis J., Gale, Michael
التنسيق: Artigo
اللغة:Inglês
منشور في: Public Library of Science 2021
الموضوعات:
Research Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC8284654/
https://ncbi.nlm.nih.gov/pubmed/34228762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009278
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