SIV infection of rhesus macaques results in dysfunctional T- and B-cell responses to neo and recall Leishmania major vaccination

HIV infection is characterized by immune system dysregulation, including depletion of CD4(+) T cells, immune activation, and abnormal B- and T-cell responses. However, the immunologic mechanisms underlying lymphocytic dysfunctionality and whether it is restricted to immune responses against neo anti...

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Detalhes bibliográficos
Main Authors: Klatt, Nichole R., Vinton, Carol L., Lynch, Rebecca M., Canary, Lauren A., Ho, Jason, Darrah, Patricia A., Estes, Jacob D., Seder, Robert A., Moir, Susan L., Brenchley, Jason M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2011
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3228497/
https://ncbi.nlm.nih.gov/pubmed/21960586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-07-365874
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