Experimental colitis in SIV-uninfected rhesus macaques recapitulates important features of pathogenic SIV infection

Mucosal damage to the gastrointestinal (GI) tract with resulting microbial translocation is hypothesized to significantly contribute to the heightened and persistent chronic inflammation and immune activation characteristic to HIV infection. Here we employ a non-human primate model of chemically ind...

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Publicado no:Nat Commun
Main Authors: Hao, Xing Pei, Lucero, Carissa M., Turkbey, Baris, Bernardo, Marcelino L., Morcock, David R., Deleage, Claire, Trubey, Charles M., Smedley, Jeremy, Klatt, Nichole R., Giavedoni, Luis D., Kristoff, Jan, Xu, Amy, Del Prete, Gregory Q., Keele, Brandon F., Rao, Srinivas S., Alvord, W. Gregory, Choyke, Peter L., Lifson, Jeffrey D., Brenchley, Jason M., Apetrei, Cristian, Pandrea, Ivona, Estes, Jacob D.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4544774/
https://ncbi.nlm.nih.gov/pubmed/26282376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9020
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