Experimental colitis in SIV-uninfected rhesus macaques recapitulates important features of pathogenic SIV infection

Mucosal damage to the gastrointestinal (GI) tract with resulting microbial translocation is hypothesized to significantly contribute to the heightened and persistent chronic inflammation and immune activation characteristic to HIV infection. Here we employ a non-human primate model of chemically ind...

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Bibliografiska uppgifter
I publikationen:Nat Commun
Huvudupphovsmän: Hao, Xing Pei, Lucero, Carissa M., Turkbey, Baris, Bernardo, Marcelino L., Morcock, David R., Deleage, Claire, Trubey, Charles M., Smedley, Jeremy, Klatt, Nichole R., Giavedoni, Luis D., Kristoff, Jan, Xu, Amy, Del Prete, Gregory Q., Keele, Brandon F., Rao, Srinivas S., Alvord, W. Gregory, Choyke, Peter L., Lifson, Jeffrey D., Brenchley, Jason M., Apetrei, Cristian, Pandrea, Ivona, Estes, Jacob D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Pub. Group 2015
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4544774/
https://ncbi.nlm.nih.gov/pubmed/26282376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9020
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