Downregulation of Robust Acute Type I Interferon Responses Distinguishes Nonpathogenic Simian Immunodeficiency Virus (SIV) Infection of Natural Hosts from Pathogenic SIV Infection of Rhesus Macaques

The mechanisms underlying the AIDS resistance of natural hosts for simian immunodeficiency virus (SIV) remain unknown. Recently, it was proposed that natural SIV hosts avoid disease because their plasmacytoid dendritic cells (pDCs) are intrinsically unable to produce alpha interferon (IFN-α) in resp...

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Xehetasun bibliografikoak
Egile Nagusiak: Harris, Levelle D., Tabb, Brian, Sodora, Donald L., Paiardini, Mirko, Klatt, Nichole R., Douek, Daniel C., Silvestri, Guido, Müller-Trutwin, Michaela, Vasile-Pandrea, Ivona, Apetrei, Cristian, Hirsch, Vanessa, Lifson, Jeffrey, Brenchley, Jason M., Estes, Jacob D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology (ASM) 2010
Gaiak:
Pathogenesis and Immunity
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897601/
https://ncbi.nlm.nih.gov/pubmed/20484518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02612-09
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