Downregulation of Robust Acute Type I Interferon Responses Distinguishes Nonpathogenic Simian Immunodeficiency Virus (SIV) Infection of Natural Hosts from Pathogenic SIV Infection of Rhesus Macaques

The mechanisms underlying the AIDS resistance of natural hosts for simian immunodeficiency virus (SIV) remain unknown. Recently, it was proposed that natural SIV hosts avoid disease because their plasmacytoid dendritic cells (pDCs) are intrinsically unable to produce alpha interferon (IFN-α) in resp...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Harris, Levelle D., Tabb, Brian, Sodora, Donald L., Paiardini, Mirko, Klatt, Nichole R., Douek, Daniel C., Silvestri, Guido, Müller-Trutwin, Michaela, Vasile-Pandrea, Ivona, Apetrei, Cristian, Hirsch, Vanessa, Lifson, Jeffrey, Brenchley, Jason M., Estes, Jacob D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897601/
https://ncbi.nlm.nih.gov/pubmed/20484518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02612-09
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados