Damaged Intestinal Epithelial Integrity Linked to Microbial Translocation in Pathogenic Simian Immunodeficiency Virus Infections

The chronic phase of HIV infection is marked by pathological activation of the immune system, the extent of which better predicts disease progression than either plasma viral load or CD4(+) T cell count. Recently, translocation of microbial products from the gastrointestinal tract has been proposed...

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Detalhes bibliográficos
Main Authors: Estes, Jacob D., Harris, Levelle D., Klatt, Nichole R., Tabb, Brian, Pittaluga, Stefania, Paiardini, Mirko, Barclay, G. Robin, Smedley, Jeremy, Pung, Rhonda, Oliveira, Kenneth M., Hirsch, Vanessa M., Silvestri, Guido, Douek, Daniel C., Miller, Christopher J., Haase, Ashley T., Lifson, Jeffrey, Brenchley, Jason M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924359/
https://ncbi.nlm.nih.gov/pubmed/20808901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001052
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