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The Regulation of Th1 Responses by the p38 MAPK
IL-12 is a dimeric cytokine that is produced primarily by APCs. In this study we examined the role that the p38 MAPKs (MAPK/p38) play in regulating IL-12 production. We show that inhibition of p38 dramatically increased IL-12 production upon stimulation, while decreasing TNF-α. This reciprocal effec...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3050061/ https://ncbi.nlm.nih.gov/pubmed/20937847 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000243 |
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