Overcoming immunological barriers in regenerative medicine

по Zakrzewski, Johannes L, van den Brink, Marcel R M, Hubbell, Jeffrey A
Опубликовано в: Nat Biotechnol (2014)

Enhancing T cell reconstitution after hematopoietic stem cell transplantation: a brief update of the latest trends

по Zakrzewski, Johannes L., Goldberg, Gabrielle L., Smith, Odette M., van den Brink, Marcel R.M.
Опубликовано 2007

Clinical Strategies to Enhance T cell Reconstitution

по Goldberg, Gabrielle L, Zakrzewski, Johannes L, Perales, Miguel A, van den Brink, Marcel R.M.
Опубликовано 2007

Free-hand ultrasound guidance permits safe and efficient minimally invasive intrathymic injections in both young and aged mice

по Tuckett, Andrea Z., Zakrzewski, Johannes L., Li, Duan, van den Brink, Marcel R.M., Thornton, Raymond H.
Опубликовано в: Ultrasound Med Biol (2015)

Adoptive precursor cell therapy to enhance immune reconstitution after hematopoietic stem cell transplantation in mouse and man

по Holland, Amanda M., Zakrzewski, Johannes L., Goldberg, Gabrielle L., Ghosh, Arnab, van den Brink, Marcel R. M.
Опубликовано в: Semin Immunopathol (2008)

Intrathymic injection of hematopoietic progenitor cells establishes functional T cell development in a mouse model of severe combined immunodeficiency

по Tuckett, Andrea Z., Thornton, Raymond H., O’Reilly, Richard J., van den Brink, Marcel R. M., Zakrzewski, Johannes L.
Опубликовано в: J Hematol Oncol (2017)

Image-guided intrathymic injection of multipotent stem cells supports lifelong T-cell immunity and facilitates targeted immunotherapy

по Tuckett, Andrea Z., Thornton, Raymond H., Shono, Yusuke, Smith, Odette M., Levy, Emily R., Kreines, Fabiana M., van den Brink, Marcel R. M., Zakrzewski, Johannes L.
Опубликовано 2014

Targeting metabolism and survival in chronic lymphocytic leukemia and Richter syndrome cells by a novel NF-κB inhibitor

по Vaisitti, Tiziana, Gaudino, Federica, Ouk, Samedy, Moscvin, Maria, Vitale, Nicoletta, Serra, Sara, Arruga, Francesca, Zakrzewski, Johannes L., Liou, Hsiou-Chi, Allan, John N., Furman, Richard R., Deaglio, Silvia
Опубликовано в: Haematologica (2017)

Extrathymic development of murine T cells after bone marrow transplantation

по Holland, Amanda M., Zakrzewski, Johannes L., Tsai, Jennifer J., Hanash, Alan M., Dudakov, Jarrod A., Smith, Odette M., West, Mallory L., Singer, Natalie V., Brill, Jessie, Sun, Joseph C., van den Brink, Marcel R.M.
Опубликовано 2012

Organ-derived dendritic cells have differential effects on alloreactive T cells

по Kim, Theo D., Terwey, Theis H., Zakrzewski, Johannes L., Suh, David, Kochman, Adam A., Chen, Megan E., King, Chris G., Borsotti, Chiara, Grubin, Jeremy, Smith, Odette M., Heller, Glenn, Liu, Chen, Murphy, George F., Alpdogan, Onder, van den Brink, Marcel R. M.
Опубликовано 2008

CCR2 is required for CD8-induced graft-versus-host disease

по Terwey, Theis H., Kim, Theo D., Kochman, Adam A., Hubbard, Vanessa M., Lu, Sydney, Zakrzewski, Johannes L., Ramirez-Montagut, Teresa, Eng, Jeffrey M., Muriglan, Stephanie J., Heller, Glenn, Murphy, George F., Liu, Chen, Budak-Alpdogan, Tulin, Alpdogan, Onder, van den Brink, Marcel R. M.
Опубликовано 2005

STAT-3 and ERK 1/2 phosphorylation are critical for T-cell alloactivation and graft-versus-host disease

по Lu, Sydney X., Alpdogan, Onder, Lin, Janine, Balderas, Robert, Campos-Gonzalez, Roberto, Wang, Xiao, Gao, Guo-Jian, Suh, David, King, Christopher, Chow, Melanie, Smith, Odette M., Hubbard, Vanessa M., Bautista, Johanne L., Cabrera-Perez, Javier, Zakrzewski, Johannes L., Kochman, Adam A., Chow, Andrew, Altan-Bonnet, Gregoire, van den Brink, Marcel R. M.
Опубликовано 2008

Sex steroid blockade enhances thymopoiesis by modulating Notch signaling

по Velardi, Enrico, Tsai, Jennifer J., Holland, Amanda M., Wertheimer, Tobias, Yu, Vionnie W.C., Zakrzewski, Johannes L., Tuckett, Andrea Z., Singer, Natalie V., West, Mallory L., Smith, Odette M., Young, Lauren F., Kreines, Fabiana M., Levy, Emily R., Boyd, Richard L., Scadden, David T., Dudakov, Jarrod A., van den Brink, Marcel R.M.
Опубликовано в: J Exp Med (2014)

Characterization of a c-Rel inhibitor that mediates anticancer properties in hematologic malignancies by blocking NF-κB-controlled oxidative stress responses

по Shono, Yusuke, Tuckett, Andrea Z., Liou, Hsiou-Chi, Doubrovina, Ekaterina, Derenzini, Enrico, Ouk, Samedy, Tsai, Jennifer J., Smith, Odette M., Levy, Emily R., Kreines, Fabiana M., Ziegler, Carly G.K., Scallion, Mary I., Doubrovin, Mikhail, Heller, Glenn, Younes, Anas, O’Reilly, Richard J., van den Brink, Marcel R.M., Zakrzewski, Johannes L.
Опубликовано в: Cancer Res (2016)

A small molecule c-Rel inhibitor reduces alloactivation of T-cells without compromising anti-tumor activity

по Shono, Yusuke, Tuckett, Andrea Z, Ouk, Samedy, Liou, Hsiou-Chi, Altan-Bonnet, Grégoire, Tsai, Jennifer J, Oyler, Jennifer E, Smith, Odette M, West, Mallory L, Singer, Natalie V, Doubrovina, Ekaterina, Pankov, Dmitry, Undhad, Chandresh V, Murphy, George F, Lezcano, Cecilia, Liu, Chen, O’Reilly, Richard J, van den Brink, Marcel RM, Zakrzewski, Johannes L
Опубликовано 2014

Keratinocyte growth factor enhances DNA plasmid tumor vaccine responses after murine allogeneic bone marrow transplantation

по Jenq, Robert R., King, Christopher G., Volk, Christine, Suh, David, Smith, Odette M., Rao, Uttam K., Yim, Nury L., Holland, Amanda M., Lu, Sydney X., Zakrzewski, Johannes L., Goldberg, Gabrielle L., Diab, Adi, Alpdogan, Onder, Penack, Olaf, Na, Il-Kang, Kappel, Lucy W., Wolchok, Jedd D., Houghton, Alan N., Perales, Miguel-Angel, van den Brink, Marcel R. M.
Опубликовано 2009

Tumor immunotherapy across MHC barriers using allogeneic T-cell precursors

по Zakrzewski, Johannes L, Suh, David, Markley, John C, Smith, Odette M, King, Christopher, Goldberg, Gabrielle L, Jenq, Robert, Holland, Amanda M, Grubin, Jeremy, Cabrera-Perez, Javier, Brentjens, Renier J, Lu, Sydney X, Rizzuto, Gabrielle, Sant’Angelo, Derek B, Riviere, Isabelle, Sadelain, Michel, Heller, Glenn, Zúñiga-Pflücker, Juan Carlos, Lu, Chen, van den Brink, Marcel R M
Опубликовано 2008

Absence of P-selectin in Recipients of Allogeneic Bone Marrow Transplantation Ameliorates Experimental Graft-versus-Host-Disease

по Lu, Sydney X., Holland, Amanda M., Na, Il-Kang, Terwey, Theis H., Alpdogan, Onder, Bautista, Jhoanne L., Smith, Odette M., Suh, David, King, Christopher, Kochman, Adam, Hubbard, Vanessa M., Rao, Uttam K., Yim, Nury, Liu, Chen, Laga, Alvaro C., Murphy, George, Jenq, Robert, Zakrzewski, Johannes L., Penack, Olaf, Dykstra, Lindsay, Bampoe, Kevin, Perez, Lia, Furie, Bruce, Furie, Barbara, van den Brink, Marcel R.M.
Опубликовано 2010

Donor CD19-CAR T Cells Exert Potent Graft-versus-Lymphoma Activity With Diminished Graft-versus-Host Activity

по Ghosh, Arnab, Smith, Melody, James, Scott E., Davila, Marco L., Velardi, Enrico, Argyropoulos, Kimon V., Gunset, Gertrude, Perna, Fabiana, Kreines, Fabiana M., Levy, Emily R., Lieberman, Sophie, Jay, Hilary, Tuckett, Andrea Z., Zakrzewski, Johannes L., Tan, Lisa, Young, Lauren F., Takvorian, Kate, Dudakov, Jarrod A., Jenq, Robert R., Hanash, Alan M., Motta, Ana Carolina F., Murphy, George F., Liu, Chen, Schietinger, Andrea, Sadelain, Michel, van den Brink, Marcel R.M.
Опубликовано в: Nat Med (2017)

c-Rel orchestrates energy-dependant epithelial and macrophage reprogramming in fibrosis

по Leslie, Jack, Macia, Marina García, Luli, Saimir, Worrell, Julie C., Reilly, William J, Paish, Hannah L, Knox, Amber, Barksby, Ben S, Gee, Lucy M, Zaki, Marco Y.W., Collins, Amy, Burgoyne, Rachel A, Cameron, Rainie, Bragg, Charlotte, Xu, Xin, Chung, Git W, Brown, Colin DA, Blanchard, Andrew D, Nanthakumar, Carmel B, Karsdal, Morten, Robinson, Stuart M, Manas, Derek M, Sen, Gourab, French, Jeremy, White, Steven A, Murphy, Sandra, Trost, Matthias, Zakrzewski, Johannes L, Klein, Ulf, Schwabe, Robert F, Mederacke, Ingmar, Nixon, Colin, Bird, Tom, Teuwen, Laure-Anne, Schoonjans, Luc, Carmeliet, Peter, Mann, Jelena, Fisher, Andrew J, Sheerin, Neil S, Borthwick, Lee A, Mann, Derek A, Oakley, Fiona
Опубликовано в: Nat Metab (2020)