Rejuvenation of the aging T cell compartment

Por Holland, Amanda M., van den Brink, Marcel R.M.
Publicado em 2009

Genetically engineered donor T cells to optimize graft-versus-tumor effects across MHC barriers

Por Ghosh, Arnab, Holland, Amanda M., van den Brink, Marcel R.M.
Publicado em 2014

Adoptive precursor cell therapy to enhance immune reconstitution after hematopoietic stem cell transplantation in mouse and man

Por Holland, Amanda M., Zakrzewski, Johannes L., Goldberg, Gabrielle L., Ghosh, Arnab, van den Brink, Marcel R. M.
Publicado no Semin Immunopathol (2008)

A type 2 cytokine axis for thymus emigration

Por White, Andrea J., Baik, Song, Parnell, Sonia M., Holland, Amanda M., Brombacher, Frank, Jenkinson, William E., Anderson, Graham
Publicado no J Exp Med (2017)

Extrathymic development of murine T cells after bone marrow transplantation

Por Holland, Amanda M., Zakrzewski, Johannes L., Tsai, Jennifer J., Hanash, Alan M., Dudakov, Jarrod A., Smith, Odette M., West, Mallory L., Singer, Natalie V., Brill, Jessie, Sun, Joseph C., van den Brink, Marcel R.M.
Publicado em 2012

IL-17 contributes to CD4-mediated graft-versus-host disease

Por Kappel, Lucy W., Goldberg, Gabrielle L., King, Christopher G., Suh, David Y., Smith, Odette M., Ligh, Cassandra, Holland, Amanda M., Grubin, Jeremy, Mark, Nicholas M., Liu, Chen, Iwakura, Yoichiro, Heller, Glenn, van den Brink, Marcel R. M.
Publicado em 2009

Interleukin-22 drives endogenous thymic regeneration in mice

Por Dudakov, Jarrod A., Hanash, Alan M., Jenq, Robert R., Young, Lauren F., Ghosh, Arnab, Singer, Natalie V., West, Mallory L., Smith, Odette M., Holland, Amanda M., Tsai, Jennifer J., Boyd, Richard L., van den Brink, Marcel R.M.
Publicado em 2012

NOD2 regulates hematopoietic cell function during graft-versus-host disease

Por Penack, Olaf, Smith, Odette M., Cunningham-Bussel, Amy, Liu, Xin, Rao, Uttam, Yim, Nury, Na, Il-Kang, Holland, Amanda M., Ghosh, Arnab, Lu, Sydney X., Jenq, Robert R., Liu, Chen, Murphy, George F., Brandl, Katharina, van den Brink, Marcel R.M.
Publicado em 2009

Concurrent visualization of trafficking, expansion, and activation of T lymphocytes and T-cell precursors in vivo

Por Na, Il-Kang, Markley, John C., Tsai, Jennifer J., Yim, Nury L., Beattie, Bradley J., Klose, Alexander D., Holland, Amanda M., Ghosh, Arnab, Rao, Uttam K., Stephan, Matthias T., Serganova, Inna, Santos, Elmer B., Brentjens, Renier J., Blasberg, Ronald G., Sadelain, Michel, van den Brink, Marcel R. M.
Publicado em 2010

Nrf2 regulates haematopoietic stem cell function

Por Tsai, Jennifer J., Dudakov, Jarrod A., Takahashi, Koichi, Shieh, Jae-Hung, Velardi, Enrico, Holland, Amanda M., Singer, Natalie V., West, Mallory L., Smith, Odette M., Young, Lauren F., Shono, Yusuke, Ghosh, Arnab, Hanash, Alan M., Tran, Hien T., Moore, Malcolm A.S., van den Brink, Marcel R.M.
Publicado em 2013

Abrogation of donor T-cell IL-21 signaling leads to tissue-specific modulation of immunity and separation of GVHD from GVL

Por Hanash, Alan M., Kappel, Lucy W., Yim, Nury L., Nejat, Rebecca A., Goldberg, Gabrielle L., Smith, Odette M., Rao, Uttam K., Dykstra, Lindsay, Na, Il-Kang, Holland, Amanda M., Dudakov, Jarrod A., Liu, Chen, Murphy, George F., Leonard, Warren J., Heller, Glenn, van den Brink, Marcel R. M.
Publicado em 2011

Inhibition of Neovascularization to Simultaneously Ameliorate Graft-vs-Host Disease and Decrease Tumor Growth

Por Penack, Olaf, Henke, Erik, Suh, David, King, Chris G., Smith, Odette M., Na, Il-Kang, Holland, Amanda M., Ghosh, Arnab, Lu, Sydney X., Jenq, Robert R., Liu, Chen, Murphy, George F., Lu, Theresa T., May, Chad, Scheinberg, David A., Gao, Ding Cheng, Mittal, Vivek, Heller, Glenn, Benezra, Robert, van den Brink, Marcel R. M.
Publicado em 2010

Sex steroid blockade enhances thymopoiesis by modulating Notch signaling

Por Velardi, Enrico, Tsai, Jennifer J., Holland, Amanda M., Wertheimer, Tobias, Yu, Vionnie W.C., Zakrzewski, Johannes L., Tuckett, Andrea Z., Singer, Natalie V., West, Mallory L., Smith, Odette M., Young, Lauren F., Kreines, Fabiana M., Levy, Emily R., Boyd, Richard L., Scadden, David T., Dudakov, Jarrod A., van den Brink, Marcel R.M.
Publicado no J Exp Med (2014)

Keratinocyte growth factor enhances DNA plasmid tumor vaccine responses after murine allogeneic bone marrow transplantation

Por Jenq, Robert R., King, Christopher G., Volk, Christine, Suh, David, Smith, Odette M., Rao, Uttam K., Yim, Nury L., Holland, Amanda M., Lu, Sydney X., Zakrzewski, Johannes L., Goldberg, Gabrielle L., Diab, Adi, Alpdogan, Onder, Penack, Olaf, Na, Il-Kang, Kappel, Lucy W., Wolchok, Jedd D., Houghton, Alan N., Perales, Miguel-Angel, van den Brink, Marcel R. M.
Publicado em 2009

Tumor immunotherapy across MHC barriers using allogeneic T-cell precursors

Por Zakrzewski, Johannes L, Suh, David, Markley, John C, Smith, Odette M, King, Christopher, Goldberg, Gabrielle L, Jenq, Robert, Holland, Amanda M, Grubin, Jeremy, Cabrera-Perez, Javier, Brentjens, Renier J, Lu, Sydney X, Rizzuto, Gabrielle, Sant’Angelo, Derek B, Riviere, Isabelle, Sadelain, Michel, Heller, Glenn, Zúñiga-Pflücker, Juan Carlos, Lu, Chen, van den Brink, Marcel R M
Publicado em 2008

The cytolytic molecules Fas ligand and TRAIL are required for murine thymic graft-versus-host disease

Por Na, Il-Kang, Lu, Sydney X., Yim, Nury L., Goldberg, Gabrielle L., Tsai, Jennifer, Rao, Uttam, Smith, Odette M., King, Christopher G., Suh, David, Hirschhorn-Cymerman, Daniel, Palomba, Lia, Penack, Olaf, Holland, Amanda M., Jenq, Robert R., Ghosh, Arnab, Tran, Hien, Merghoub, Taha, Liu, Chen, Sempowski, Gregory D., Ventevogel, Melissa, Beauchemin, Nicole, van den Brink, Marcel R.M.
Publicado em 2009

PLZF confers effector functions to donor T cells that preserve graft-versus-tumor effects while attenuating graft-versus-host-disease

Por Ghosh, Arnab, Holland, Amanda M., Dogan, Yildirim, Yim, Nury L., Rao, Uttam K., Young, Lauren F., West, Mallory L., Singer, Natalie V., Lee, Hae, Na, Il-Kang, Tsai, Jennifer J., Jenq, Robert R., Penack, Olaf, Hanash, Alan M., Lezcano, Cecilia, Murphy, George, Liu, Chen, Sadelain, Michel, Sauer, Martin G., Sant’Angelo, Derek, van den Brink, Marcel R.M.
Publicado em 2013

Adoptively transferred TRAIL(+) T cells suppress GVHD and augment antitumor activity

Por Ghosh, Arnab, Dogan, Yildirim, Moroz, Maxim, Holland, Amanda M., Yim, Nury L., Rao, Uttam K., Young, Lauren F., Tannenbaum, Daniel, Masih, Durva, Velardi, Enrico, Tsai, Jennifer J., Jenq, Robert R., Penack, Olaf, Hanash, Alan M., Smith, Odette M., Piersanti, Kelly, Lezcano, Cecilia, Murphy, George F., Liu, Chen, Palomba, M. Lia, Sauer, Martin G., Sadelain, Michel, Ponomarev, Vladimir, van den Brink, Marcel R.M.
Publicado em 2013

Ceacam1 Separates Graft-versus-Host-Disease from Graft-versus-Tumor Activity after Experimental Allogeneic Bone Marrow Transplantation

Por Lu, Sydney X., Kappel, Lucy W., Charbonneau-Allard, Anne-Marie, Atallah, Renée, Holland, Amanda M., Turbide, Claire, Hubbard, Vanessa M., Rotolo, Jimmy A., Smith, Marsinay, Suh, David, King, Christopher, Rao, Uttam K., Yim, Nury, Bautista, Johanne L., Jenq, Robert R., Penack, Olaf, Na, Il-Kang, Liu, Chen, Murphy, George, Alpdogan, Onder, Blumberg, Richard S., Macian, Fernando, Holmes, Kathryn V., Beauchemin, Nicole, van den Brink, Marcel R. M.
Publicado em 2011

Interleukin-22 protects intestinal stem cells from immune-mediated tissue damage and regulates sensitivity to graft vs. host disease

Por Hanash, Alan M., Dudakov, Jarrod A., Hua, Guoqiang, O’Connor, Margaret H., Young, Lauren F., Singer, Natalie V., West, Mallory L., Jenq, Robert R., Holland, Amanda M., Kappel, Lucy W., Ghosh, Arnab, Tsai, Jennifer J., Rao, Uttam K., Yim, Nury L., Smith, Odette M., Velardi, Enrico, Hawryluk, Elena, Murphy, George F., Liu, Chen, Fouser, Lynette A., Kolesnick, Richard, Blazar, Bruce R., van den Brink, Marcel R.M.
Publicado em 2012