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Sex steroid blockade enhances thymopoiesis by modulating Notch signaling
Paradoxical to its importance for generating a diverse T cell repertoire, thymic function progressively declines throughout life. This process has been at least partially attributed to the effects of sex steroids, and their removal promotes enhanced thymopoiesis and recovery from immune injury. We s...
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| Pubblicato in: | J Exp Med |
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| Autori principali: | , , , , , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Rockefeller University Press
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4235646/ https://ncbi.nlm.nih.gov/pubmed/25332287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20131289 |
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