Loss of thymic innate lymphoid cells leads to impaired thymopoiesis in experimental graft-versus-host disease

Graft-versus-host disease (GVHD) and posttransplant immunodeficiency are frequently related complications of allogeneic hematopoietic transplantation. Alloreactive donor T cells can damage thymic epithelium, thus limiting new T-cell development. Although the thymus has a remarkable capacity to regen...

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Bibliografske podrobnosti
izdano v:Blood
Main Authors: Dudakov, Jarrod A., Mertelsmann, Anna M., O’Connor, Margaret H., Jenq, Robert R., Velardi, Enrico, Young, Lauren F., Smith, Odette M., Boyd, Richard L., van den Brink, Marcel R. M., Hanash, Alan M.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2017
Teme:
Transplantation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5561900/
https://ncbi.nlm.nih.gov/pubmed/28607133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-01-762658
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