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Clinical strategies to enhance thymic recovery after allogeneic hematopoietic stem cell transplantation

Despite its critical role in supplying naïve T cells to the circulation, the thymus is particularly sensitive to immune injury, such as that caused by cytoreductive chemo- or radiation therapy, shock, infection and graft versus host disease (GVHD). Crucially, insufficient thymic recovery has been di...

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Библиографические подробности
Главные авторы: Velardi, Enrico, Dudakov, Jarrod A., van den Brink, Marcel R.M.
Формат: Artigo
Язык:Inglês
Опубликовано: 2013
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871183/
https://ncbi.nlm.nih.gov/pubmed/24120996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imlet.2013.09.016
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