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Interleukin-22 drives endogenous thymic regeneration in mice

Endogenous thymic regeneration is a crucial function that allows for renewal of immune competence after stress, infection or immunodepletion. The mechanisms governing this regeneration, however, remain poorly understood. Here we detail a framework of thymic regeneration centred on IL-22 and triggere...

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Detalhes bibliográficos
Main Authors: Dudakov, Jarrod A., Hanash, Alan M., Jenq, Robert R., Young, Lauren F., Ghosh, Arnab, Singer, Natalie V., West, Mallory L., Smith, Odette M., Holland, Amanda M., Tsai, Jennifer J., Boyd, Richard L., van den Brink, Marcel R.M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616391/
https://ncbi.nlm.nih.gov/pubmed/22383805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1218004
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