Loss of thymic innate lymphoid cells leads to impaired thymopoiesis in experimental graft-versus-host disease

Graft-versus-host disease (GVHD) and posttransplant immunodeficiency are frequently related complications of allogeneic hematopoietic transplantation. Alloreactive donor T cells can damage thymic epithelium, thus limiting new T-cell development. Although the thymus has a remarkable capacity to regen...

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Dettagli Bibliografici
Pubblicato in:Blood
Autori principali: Dudakov, Jarrod A., Mertelsmann, Anna M., O’Connor, Margaret H., Jenq, Robert R., Velardi, Enrico, Young, Lauren F., Smith, Odette M., Boyd, Richard L., van den Brink, Marcel R. M., Hanash, Alan M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2017
Soggetti:
Transplantation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5561900/
https://ncbi.nlm.nih.gov/pubmed/28607133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-01-762658
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