Extrathymic development of murine T cells after bone marrow transplantation

Restoring T cell competence is a significant clinical challenge in patients whose thymic function is severely compromised due to age or cytoreductive conditioning. Here, we demonstrate in mice that mesenteric LNs (MLNs) support extrathymic T cell development in euthymic and athymic recipients of bon...

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Bibliografski detalji
Glavni autori: Holland, Amanda M., Zakrzewski, Johannes L., Tsai, Jennifer J., Hanash, Alan M., Dudakov, Jarrod A., Smith, Odette M., West, Mallory L., Singer, Natalie V., Brill, Jessie, Sun, Joseph C., van den Brink, Marcel R.M.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2012
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533530/
https://ncbi.nlm.nih.gov/pubmed/23160195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI60630
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