Extrathymic development of murine T cells after bone marrow transplantation

Restoring T cell competence is a significant clinical challenge in patients whose thymic function is severely compromised due to age or cytoreductive conditioning. Here, we demonstrate in mice that mesenteric LNs (MLNs) support extrathymic T cell development in euthymic and athymic recipients of bon...

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Detalhes bibliográficos
Main Authors: Holland, Amanda M., Zakrzewski, Johannes L., Tsai, Jennifer J., Hanash, Alan M., Dudakov, Jarrod A., Smith, Odette M., West, Mallory L., Singer, Natalie V., Brill, Jessie, Sun, Joseph C., van den Brink, Marcel R.M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533530/
https://ncbi.nlm.nih.gov/pubmed/23160195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI60630
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