Genetic drivers of vulnerability and resistance in relapsed acute lymphoblastic leukemia

Por Lu, Sydney X., Abdel-Wahab, Omar
Publicado no Proc Natl Acad Sci U S A (2016)

Relapse After Allogeneic Hematopoietic Cell Therapy

Por van den Brink, Marcel R.M., Porter, David L., Giralt, Sergio, Lu, Sydney X., Jenq, Robert R., Hanash, Alan, Bishop, Michael R.
Publicado em 2009

Absence of donor T-cell–derived soluble TNF decreases graft-versus-host disease without impairing graft-versus-tumor activity

Por Borsotti, Chiara, Franklin, Anna R. K., Lu, Sydney X., Kim, Theo D., Smith, Odette M., Suh, David, King, Chris G., Chow, Andrew, Liu, Chen, Alpdogan, Onder, van den Brink, Marcel R. M.
Publicado em 2007

Cytolytic T cells induce ceramide-rich platforms in target cell membranes to initiate graft-versus-host disease

Por Rotolo, Jimmy A., Stancevic, Branka, Lu, Sydney X., Zhang, Jianjun, Suh, David, King, Christopher G., Kappel, Lucy W., Murphy, George F., Liu, Chen, Fuks, Zvi, van den Brink, Marcel R., Kolesnick, Richard
Publicado em 2009

Rapidly proliferating CD44(hi) peripheral T cells undergo apoptosis and delay posttransplantation T-cell reconstitution after allogeneic bone marrow transplantation

Por Alpdogan, S. Önder, Lu, Sydney X., Patel, Neel, McGoldrick, Suzanne, Suh, David, Budak-Alpdogan, Tulin, Smith, Odette M., Grubin, Jeremy, King, Christopher, Goldberg, Gabrielle L., Hubbard, Vanessa M., Kochman, Adam A., van den Brink, Marcel R. M.
Publicado em 2008

Absence of β7 integrin results in less graft-versus-host disease because of decreased homing of alloreactive T cells to intestine

Por Waldman, Elisha, Lu, Sydney X., Hubbard, Vanessa M., Kochman, Adam A., Eng, Jeffrey M., Terwey, Theis H., Muriglan, Stephanie J., Kim, Theo D., Heller, Glenn, Murphy, George F., Liu, Chen, Alpdogan, Onder, van den Brink, Marcel R. M.
Publicado em 2006

NOD2 regulates hematopoietic cell function during graft-versus-host disease

Por Penack, Olaf, Smith, Odette M., Cunningham-Bussel, Amy, Liu, Xin, Rao, Uttam, Yim, Nury, Na, Il-Kang, Holland, Amanda M., Ghosh, Arnab, Lu, Sydney X., Jenq, Robert R., Liu, Chen, Murphy, George F., Brandl, Katharina, van den Brink, Marcel R.M.
Publicado em 2009

STAT-3 and ERK 1/2 phosphorylation are critical for T-cell alloactivation and graft-versus-host disease

Por Lu, Sydney X., Alpdogan, Onder, Lin, Janine, Balderas, Robert, Campos-Gonzalez, Roberto, Wang, Xiao, Gao, Guo-Jian, Suh, David, King, Christopher, Chow, Melanie, Smith, Odette M., Hubbard, Vanessa M., Bautista, Johanne L., Cabrera-Perez, Javier, Zakrzewski, Johannes L., Kochman, Adam A., Chow, Andrew, Altan-Bonnet, Gregoire, van den Brink, Marcel R. M.
Publicado em 2008

Inhibition of Neovascularization to Simultaneously Ameliorate Graft-vs-Host Disease and Decrease Tumor Growth

Por Penack, Olaf, Henke, Erik, Suh, David, King, Chris G., Smith, Odette M., Na, Il-Kang, Holland, Amanda M., Ghosh, Arnab, Lu, Sydney X., Jenq, Robert R., Liu, Chen, Murphy, George F., Lu, Theresa T., May, Chad, Scheinberg, David A., Gao, Ding Cheng, Mittal, Vivek, Heller, Glenn, Benezra, Robert, van den Brink, Marcel R. M.
Publicado em 2010

Genomic analysis of hairy cell leukemia identifies novel recurrent genetic alterations

Por Durham, Benjamin H., Getta, Bartlomiej, Dietrich, Sascha, Taylor, Justin, Won, Helen, Bogenberger, James M., Scott, Sasinya, Kim, Eunhee, Chung, Young Rock, Chung, Stephen S., Hüllein, Jennifer, Walther, Tatjana, Wang, Lu, Lu, Sydney X., Oakes, Christopher C., Tibes, Raoul, Haferlach, Torsten, Taylor, Barry S., Tallman, Martin S., Berger, Michael F., Park, Jae H., Zenz, Thorsten, Abdel-Wahab, Omar
Publicado no Blood (2017)

Keratinocyte growth factor enhances DNA plasmid tumor vaccine responses after murine allogeneic bone marrow transplantation

Por Jenq, Robert R., King, Christopher G., Volk, Christine, Suh, David, Smith, Odette M., Rao, Uttam K., Yim, Nury L., Holland, Amanda M., Lu, Sydney X., Zakrzewski, Johannes L., Goldberg, Gabrielle L., Diab, Adi, Alpdogan, Onder, Penack, Olaf, Na, Il-Kang, Kappel, Lucy W., Wolchok, Jedd D., Houghton, Alan N., Perales, Miguel-Angel, van den Brink, Marcel R. M.
Publicado em 2009

Tumor immunotherapy across MHC barriers using allogeneic T-cell precursors

Por Zakrzewski, Johannes L, Suh, David, Markley, John C, Smith, Odette M, King, Christopher, Goldberg, Gabrielle L, Jenq, Robert, Holland, Amanda M, Grubin, Jeremy, Cabrera-Perez, Javier, Brentjens, Renier J, Lu, Sydney X, Rizzuto, Gabrielle, Sant’Angelo, Derek B, Riviere, Isabelle, Sadelain, Michel, Heller, Glenn, Zúñiga-Pflücker, Juan Carlos, Lu, Chen, van den Brink, Marcel R M
Publicado em 2008

The cytolytic molecules Fas ligand and TRAIL are required for murine thymic graft-versus-host disease

Por Na, Il-Kang, Lu, Sydney X., Yim, Nury L., Goldberg, Gabrielle L., Tsai, Jennifer, Rao, Uttam, Smith, Odette M., King, Christopher G., Suh, David, Hirschhorn-Cymerman, Daniel, Palomba, Lia, Penack, Olaf, Holland, Amanda M., Jenq, Robert R., Ghosh, Arnab, Tran, Hien, Merghoub, Taha, Liu, Chen, Sempowski, Gregory D., Ventevogel, Melissa, Beauchemin, Nicole, van den Brink, Marcel R.M.
Publicado em 2009

Robust patient-derived xenografts of MDS/MPN overlap syndromes capture the unique characteristics of CMML and JMML

Por Yoshimi, Akihide, Balasis, Maria E., Vedder, Alexis, Feldman, Kira, Ma, Yan, Zhang, Hailing, Lee, Stanley Chun-Wei, Letson, Christopher, Niyongere, Sandrine, Lu, Sydney X., Ball, Markus, Taylor, Justin, Zhang, Qing, Zhao, Yulong, Youssef, Salma, Chung, Young Rock, Zhang, Xiao Jing, Durham, Benjamin H., Yang, Wendy, List, Alan F., Loh, Mignon L., Klimek, Virginia, Berger, Michael F., Stieglitz, Elliot, Padron, Eric, Abdel-Wahab, Omar
Publicado no Blood (2017)

Ceacam1 Separates Graft-versus-Host-Disease from Graft-versus-Tumor Activity after Experimental Allogeneic Bone Marrow Transplantation

Por Lu, Sydney X., Kappel, Lucy W., Charbonneau-Allard, Anne-Marie, Atallah, Renée, Holland, Amanda M., Turbide, Claire, Hubbard, Vanessa M., Rotolo, Jimmy A., Smith, Marsinay, Suh, David, King, Christopher, Rao, Uttam K., Yim, Nury, Bautista, Johanne L., Jenq, Robert R., Penack, Olaf, Na, Il-Kang, Liu, Chen, Murphy, George, Alpdogan, Onder, Blumberg, Richard S., Macian, Fernando, Holmes, Kathryn V., Beauchemin, Nicole, van den Brink, Marcel R. M.
Publicado em 2011

Absence of P-selectin in Recipients of Allogeneic Bone Marrow Transplantation Ameliorates Experimental Graft-versus-Host-Disease

Por Lu, Sydney X., Holland, Amanda M., Na, Il-Kang, Terwey, Theis H., Alpdogan, Onder, Bautista, Jhoanne L., Smith, Odette M., Suh, David, King, Christopher, Kochman, Adam, Hubbard, Vanessa M., Rao, Uttam K., Yim, Nury, Liu, Chen, Laga, Alvaro C., Murphy, George, Jenq, Robert, Zakrzewski, Johannes L., Penack, Olaf, Dykstra, Lindsay, Bampoe, Kevin, Perez, Lia, Furie, Bruce, Furie, Barbara, van den Brink, Marcel R.M.
Publicado em 2010